deltatrials
Recruiting OBSERVATIONAL NCT02434393

Characterizing Cognitive Decline in Late Life Depression: The ADNI Depression Project (ADNI-D)

Characterizing Cognitive Decline in Late Life Depression: The Alzheimer's Disease Neuroimaging Initiative - Depression Project

Sponsor: Alzheimer's Therapeutic Research Institute

Conditions Late Life Depression (LLD) Major Depression
Updated 17 times since 2017 Last updated: Nov 21, 2025 Started: Mar 4, 2015 Primary completion: May 31, 2027 Completion: May 31, 2027
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A observational or N/A phase clinical study on Late Life Depression (LLD) and Major Depression, this trial is actively recruiting participants. The trial is conducted by Alzheimer's Therapeutic Research Institute and has accumulated 17 data snapshots since 2015. Psychiatric clinical trials are essential for establishing evidence-based treatment standards.

Status Flow

~Jan 2017 – ~Aug 2017 · 7 months · monthly snapshot~Aug 2017 – ~Dec 2017 · 4 months · monthly snapshot~Dec 2017 – ~Apr 2018 · 4 months · monthly snapshot~Apr 2018 – ~May 2018 · 30 days · monthly snapshot~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Mar 2019 · 9 months · monthly snapshot~Mar 2019 – ~Nov 2020 · 20 months · monthly snapshot~Nov 2020 – ~Dec 2020 · 30 days · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Dec 2021 · 11 months · monthly snapshot~Dec 2021 – ~Jun 2022 · 6 months · monthly snapshot~Jun 2022 – ~Nov 2022 · 5 months · monthly snapshot~Nov 2022 – ~Jul 2024 · 20 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Nov 2024 · 2 months · monthly snapshot~Nov 2024 – ~Dec 2025 · 13 months · monthly snapshot~Dec 2025 – present · 7 months · monthly snapshot

Change History

17 versions recorded

  1. Dec 2025 — Present [monthly]

    Recruiting

  2. Nov 2024 — Dec 2025 [monthly]

    Recruiting

    Status: Active Not Recruiting → Recruiting

  3. Sep 2024 — Nov 2024 [monthly]

    Active Not Recruiting

  4. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting

  5. Nov 2022 — Jul 2024 [monthly]

    Active Not Recruiting

▶ Show 12 earlier versions

  1. Jun 2022 — Nov 2022 [monthly]

    Active Not Recruiting

  2. Dec 2021 — Jun 2022 [monthly]

    Active Not Recruiting

  3. Jan 2021 — Dec 2021 [monthly]

    Active Not Recruiting

  4. Dec 2020 — Jan 2021 [monthly]

    Active Not Recruiting

  5. Nov 2020 — Dec 2020 [monthly]

    Active Not Recruiting

  6. Mar 2019 — Nov 2020 [monthly]

    Active Not Recruiting

  7. Jun 2018 — Mar 2019 [monthly]

    Active Not Recruiting

  8. May 2018 — Jun 2018 [monthly]

    Active Not Recruiting

  9. Apr 2018 — May 2018 [monthly]

    Active Not Recruiting

    Phase: NA → None

  10. Dec 2017 — Apr 2018 [monthly]

    Active Not Recruiting NA

    Status: Recruiting → Active Not Recruiting

  11. Aug 2017 — Dec 2017 [monthly]

    Recruiting NA

  12. Jan 2017 — Aug 2017 [monthly]

    Recruiting NA

    First recorded

Mar 2015

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Alzheimer's Therapeutic Research Institute
  • National Institute of Mental Health (NIMH)
  • University of California, San Francisco
  • University of Southern California
Data source: University of Southern California

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations