deltatrials
Recruiting OBSERVATIONAL NCT02461446

Natural History Study of Individuals With Autism and Germline Heterozygous PTEN Mutations

Sponsor: Boston Children's Hospital

Conditions ASD Autism Macrocephaly PTEN PTEN Hamartoma Tumor Syndrome
Updated 20 times since 2017 Last updated: Oct 24, 2024 Started: May 31, 2015 Primary completion: Dec 31, 2025 Completion: Dec 31, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This observational or N/A phase trial investigates ASD and Autism and is currently actively recruiting participants. Boston Children's Hospital leads this study, which shows 20 recorded versions since 2015 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jan 2017 – ~Aug 2017 · 7 months · monthly snapshot~Aug 2017 – ~Apr 2018 · 8 months · monthly snapshot~Apr 2018 – ~May 2018 · 30 days · monthly snapshot~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Dec 2018 · 6 months · monthly snapshot~Dec 2018 – ~Apr 2019 · 4 months · monthly snapshot~Apr 2019 – ~Jul 2019 · 3 months · monthly snapshot~Jul 2019 – ~Feb 2020 · 7 months · monthly snapshot~Feb 2020 – ~May 2020 · 3 months · monthly snapshot~May 2020 – ~Sep 2020 · 4 months · monthly snapshot~Sep 2020 – ~Nov 2020 · 2 months · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshot~Sep 2021 – ~Dec 2021 · 3 months · monthly snapshot~Dec 2021 – ~Sep 2022 · 9 months · monthly snapshot~Sep 2022 – ~Dec 2023 · 15 months · monthly snapshot~Dec 2023 – ~Jul 2024 · 7 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Nov 2024 · 2 months · monthly snapshot~Nov 2024 – present · 20 months · monthly snapshot

Change History

20 versions recorded

  1. Nov 2024 — Present [monthly]

    Recruiting

  2. Sep 2024 — Nov 2024 [monthly]

    Recruiting

  3. Jul 2024 — Sep 2024 [monthly]

    Recruiting

  4. Dec 2023 — Jul 2024 [monthly]

    Recruiting

  5. Sep 2022 — Dec 2023 [monthly]

    Recruiting

▶ Show 15 earlier versions

  1. Dec 2021 — Sep 2022 [monthly]

    Recruiting

  2. Sep 2021 — Dec 2021 [monthly]

    Recruiting

  3. Jan 2021 — Sep 2021 [monthly]

    Recruiting

  4. Nov 2020 — Jan 2021 [monthly]

    Recruiting

  5. Sep 2020 — Nov 2020 [monthly]

    Recruiting

  6. May 2020 — Sep 2020 [monthly]

    Recruiting

    Status: Active Not Recruiting → Recruiting

  7. Feb 2020 — May 2020 [monthly]

    Active Not Recruiting

  8. Jul 2019 — Feb 2020 [monthly]

    Active Not Recruiting

  9. Apr 2019 — Jul 2019 [monthly]

    Active Not Recruiting

  10. Dec 2018 — Apr 2019 [monthly]

    Active Not Recruiting

    Status: Recruiting → Active Not Recruiting

  11. Jun 2018 — Dec 2018 [monthly]

    Recruiting

  12. May 2018 — Jun 2018 [monthly]

    Recruiting

  13. Apr 2018 — May 2018 [monthly]

    Recruiting

    Phase: NA → None

  14. Aug 2017 — Apr 2018 [monthly]

    Recruiting NA

  15. Jan 2017 — Aug 2017 [monthly]

    Recruiting NA

    First recorded

May 2015

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Boston Children's Hospital
  • Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
  • National Center for Advancing Translational Sciences (NCATS)
  • National Institute of Neurological Disorders and Stroke (NINDS)
  • National Institutes of Health (NIH)
  • Office of Rare Diseases (ORD)
Data source: Boston Children's Hospital

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations