deltatrials
Completed PHASE2 INTERVENTIONAL 1-arm NCT02493036

A Single-Dose, Open-Label, Study to Evaluate the Sustainability of the Effects of SYN-010 in Patients With IBS-C

A Single-Dose, Open-Label, Extension Study to Evaluate the Sustainability of the Effects of SYN-010 in Patients With Irritable Bowel Syndrome With Constipation

Sponsor: Theriva Biologics, Inc.

Conditions Irritable Bowel Syndrome With Constipation (IBS-C)
Interventions SYN-010
Updated 13 times since 2017 Last updated: Oct 31, 2018 Started: Oct 31, 2015 Primary completion: Dec 31, 2015 Completion: Dec 31, 2015
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Irritable Bowel Syndrome With Constipation (IBS-C) and is currently completed. Theriva Biologics, Inc. leads this study, which shows 13 recorded versions since 2015 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~May 2017 · 3 months · monthly snapshot~May 2017 – ~Jul 2017 · 2 months · monthly snapshot~Jul 2017 – ~Jun 2018 · 11 months · monthly snapshot~Jun 2018 – ~Dec 2018 · 6 months · monthly snapshot~Dec 2018 – ~Jan 2021 · 25 months · monthly snapshot~Jan 2021 – ~Dec 2022 · 23 months · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Apr 2023 · 3 months · monthly snapshot~Apr 2023 – ~Jul 2024 · 15 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 12 months · monthly snapshot

Change History

13 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  4. Apr 2023 — Jul 2024 [monthly]

    Completed PHASE2

  5. Jan 2023 — Apr 2023 [monthly]

    Completed PHASE2

▶ Show 8 earlier versions

  1. Dec 2022 — Jan 2023 [monthly]

    Completed PHASE2

  2. Jan 2021 — Dec 2022 [monthly]

    Completed PHASE2

  3. Dec 2018 — Jan 2021 [monthly]

    Completed PHASE2

  4. Jun 2018 — Dec 2018 [monthly]

    Completed PHASE2

  5. Jul 2017 — Jun 2018 [monthly]

    Completed PHASE2

  6. May 2017 — Jul 2017 [monthly]

    Completed PHASE2

  7. Feb 2017 — May 2017 [monthly]

    Completed PHASE2

  8. Jan 2017 — Feb 2017 [monthly]

    Completed PHASE2

    First recorded

Oct 2015

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Theriva Biologics, Inc.
Data source: Theriva Biologics, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations