deltatrials
Active Not Recruiting PHASE1/PHASE2 INTERVENTIONAL 6-arm NCT04692181

SYN-004 Safety and Tolerability in Allo-HCT Subjects

Phase 1b/2a Evaluation of the Safety and Tolerability of SYN-004 in Adult Allogeneic Hematopoietic Cell Transplantation (Allo-HCT) Recipients

Sponsor: Theriva Biologics, Inc.

Updated 11 times since 2021 Last updated: Jan 3, 2025 Started: Feb 15, 2021 Primary completion: Dec 31, 2025 Completion: Dec 31, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1/PHASE2 clinical study on Acute Graft-Versus-Host Reaction Following Bone Marrow Transplant and Prevention of CDI in Adult Patients Being Treated With IV Beta-lactam Antibiotics, this trial is ongoing. The trial is conducted by Theriva Biologics, Inc. and has accumulated 11 data snapshots since 2021. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshotNot Yet Recruiting~Feb 2021 – ~Apr 2021 · 59 days · monthly snapshotNot Yet Recruiting~Apr 2021 – ~May 2022 · 13 months · monthly snapshotRecruiting~May 2022 – ~Apr 2023 · 11 months · monthly snapshotRecruiting~Apr 2023 – ~Nov 2023 · 7 months · monthly snapshotRecruiting~Nov 2023 – ~Jul 2024 · 8 months · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotRecruiting~Sep 2024 – ~Dec 2024 · 3 months · monthly snapshotRecruiting~Dec 2024 – ~Feb 2025 · 2 months · monthly snapshotActive Not Recruiting~Feb 2025 – ~Sep 2025 · 7 months · monthly snapshotActive Not Recruiting~Sep 2025 – present · 12 months · monthly snapshotActive Not Recruiting

Change History

11 versions recorded
  1. Sep 2025 — Present [monthly]

    Active Not Recruiting PHASE1/PHASE2

  2. Feb 2025 — Sep 2025 [monthly]

    Active Not Recruiting PHASE1/PHASE2

  3. Dec 2024 — Feb 2025 [monthly]

    Active Not Recruiting PHASE1/PHASE2

    Status: RecruitingActive Not Recruiting

  4. Sep 2024 — Dec 2024 [monthly]

    Recruiting PHASE1/PHASE2

  5. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE1/PHASE2

    Phase: PHASE1_PHASE2PHASE1/PHASE2

Show 6 earlier versions
  1. Nov 2023 — Jul 2024 [monthly]

    Recruiting PHASE1_PHASE2

  2. Apr 2023 — Nov 2023 [monthly]

    Recruiting PHASE1_PHASE2

  3. May 2022 — Apr 2023 [monthly]

    Recruiting PHASE1_PHASE2

  4. Apr 2021 — May 2022 [monthly]

    Recruiting PHASE1_PHASE2

    Status: Not Yet RecruitingRecruiting

  5. Feb 2021 — Apr 2021 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

  6. Jan 2021 — Feb 2021 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Theriva Biologics, Inc.
  • Washington University School of Medicine
Data source: Theriva Biologics, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations