deltatrials
Active Not Recruiting PHASE3 INTERVENTIONAL 2-arm NCT02511106

AZD9291 Versus Placebo in Patients With Stage IB-IIIA Non-small Cell Lung Carcinoma, Following Complete Tumour Resection With or Without Adjuvant Chemotherapy. (ADAURA)

A Phase III, Double-blind, Randomized, Placebo-controlled Multi-centre, Study to Assess the Efficacy and Safety of AZD9291 Versus Placebo, in Patients With Epidermal Growth Factor Receptor Mutation Positive Stage IB-IIIA Non-small Cell Lung Carcinoma, Following Complete Tumour Resection With or Without Adjuvant Chemotherapy (ADAURA).

Sponsor: AstraZeneca

Updated 45 times since 2017 Last updated: Dec 12, 2025 Started: Oct 21, 2015 Primary completion: Apr 11, 2022 Completion: Jan 31, 2029
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on Stage IB-IIIA Non-small Cell Lung Carcinoma, this trial is ongoing. The trial is conducted by AstraZeneca and has accumulated 45 data snapshots since 2015. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Mar 2017 · 28 days · monthly snapshot~Mar 2017 – ~May 2017 · 2 months · monthly snapshot~May 2017 – ~Jun 2017 · 31 days · monthly snapshot~Jun 2017 – ~Aug 2017 · 2 months · monthly snapshot~Aug 2017 – ~Sep 2017 · 31 days · monthly snapshot~Sep 2017 – ~Oct 2017 · 30 days · monthly snapshot~Oct 2017 – ~Nov 2017 · 31 days · monthly snapshot~Nov 2017 – ~Feb 2018 · 3 months · monthly snapshot~Feb 2018 – ~Apr 2018 · 59 days · monthly snapshot~Apr 2018 – ~Jun 2018 · 2 months · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Sep 2018 · 2 months · monthly snapshot~Sep 2018 – ~Oct 2018 · 30 days · monthly snapshot~Oct 2018 – ~Nov 2018 · 31 days · monthly snapshot~Nov 2018 – ~Dec 2018 · 30 days · monthly snapshot~Dec 2018 – ~Feb 2019 · 2 months · monthly snapshot~Feb 2019 – ~Apr 2019 · 59 days · monthly snapshot~Apr 2019 – ~Jul 2019 · 3 months · monthly snapshot~Jul 2019 – ~Oct 2019 · 3 months · monthly snapshot~Oct 2019 – ~Jan 2020 · 3 months · monthly snapshot~Jan 2020 – ~Apr 2020 · 3 months · monthly snapshot~Apr 2020 – ~Jul 2020 · 3 months · monthly snapshot~Jul 2020 – ~Aug 2020 · 31 days · monthly snapshot~Aug 2020 – ~Nov 2020 · 3 months · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Sep 2021 · 7 months · monthly snapshot~Sep 2021 – ~Nov 2021 · 2 months · monthly snapshot~Nov 2021 – ~Dec 2021 · 30 days · monthly snapshot~Dec 2021 – ~Mar 2022 · 3 months · monthly snapshot~Mar 2022 – ~Jun 2022 · 3 months · monthly snapshot~Jun 2022 – ~Nov 2022 · 5 months · monthly snapshot~Nov 2022 – ~Feb 2023 · 3 months · monthly snapshot~Feb 2023 – ~May 2023 · 3 months · monthly snapshot~May 2023 – ~Aug 2023 · 3 months · monthly snapshot~Aug 2023 – ~Jul 2024 · 11 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Jan 2025 · 4 months · monthly snapshot~Jan 2025 – ~May 2025 · 4 months · monthly snapshot~May 2025 – ~Jun 2025 · 31 days · monthly snapshot~Jun 2025 – ~Sep 2025 · 3 months · monthly snapshot~Sep 2025 – ~Dec 2025 · 3 months · monthly snapshot~Dec 2025 – ~Feb 2026 · 2 months · monthly snapshot~Feb 2026 – present · 7 months · monthly snapshot

Change History

45 versions recorded
  1. Feb 2026 — Present [monthly]

    Active Not Recruiting PHASE3

  2. Dec 2025 — Feb 2026 [monthly]

    Active Not Recruiting PHASE3

  3. Sep 2025 — Dec 2025 [monthly]

    Active Not Recruiting PHASE3

  4. Jun 2025 — Sep 2025 [monthly]

    Active Not Recruiting PHASE3

  5. May 2025 — Jun 2025 [monthly]

    Active Not Recruiting PHASE3

Show 40 earlier versions
  1. Jan 2025 — May 2025 [monthly]

    Active Not Recruiting PHASE3

  2. Sep 2024 — Jan 2025 [monthly]

    Active Not Recruiting PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE3

  4. Aug 2023 — Jul 2024 [monthly]

    Active Not Recruiting PHASE3

  5. May 2023 — Aug 2023 [monthly]

    Active Not Recruiting PHASE3

  6. Feb 2023 — May 2023 [monthly]

    Active Not Recruiting PHASE3

  7. Nov 2022 — Feb 2023 [monthly]

    Active Not Recruiting PHASE3

  8. Jun 2022 — Nov 2022 [monthly]

    Active Not Recruiting PHASE3

  9. Mar 2022 — Jun 2022 [monthly]

    Active Not Recruiting PHASE3

  10. Dec 2021 — Mar 2022 [monthly]

    Active Not Recruiting PHASE3

  11. Nov 2021 — Dec 2021 [monthly]

    Active Not Recruiting PHASE3

  12. Sep 2021 — Nov 2021 [monthly]

    Active Not Recruiting PHASE3

  13. Feb 2021 — Sep 2021 [monthly]

    Active Not Recruiting PHASE3

  14. Jan 2021 — Feb 2021 [monthly]

    Active Not Recruiting PHASE3

  15. Nov 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE3

  16. Aug 2020 — Nov 2020 [monthly]

    Active Not Recruiting PHASE3

  17. Jul 2020 — Aug 2020 [monthly]

    Active Not Recruiting PHASE3

  18. Apr 2020 — Jul 2020 [monthly]

    Active Not Recruiting PHASE3

  19. Jan 2020 — Apr 2020 [monthly]

    Active Not Recruiting PHASE3

  20. Oct 2019 — Jan 2020 [monthly]

    Active Not Recruiting PHASE3

  21. Jul 2019 — Oct 2019 [monthly]

    Active Not Recruiting PHASE3

  22. Apr 2019 — Jul 2019 [monthly]

    Active Not Recruiting PHASE3

    Status: RecruitingActive Not Recruiting

  23. Feb 2019 — Apr 2019 [monthly]

    Recruiting PHASE3

  24. Dec 2018 — Feb 2019 [monthly]

    Recruiting PHASE3

  25. Nov 2018 — Dec 2018 [monthly]

    Recruiting PHASE3

  26. Oct 2018 — Nov 2018 [monthly]

    Recruiting PHASE3

  27. Sep 2018 — Oct 2018 [monthly]

    Recruiting PHASE3

  28. Jul 2018 — Sep 2018 [monthly]

    Recruiting PHASE3

  29. Jun 2018 — Jul 2018 [monthly]

    Recruiting PHASE3

  30. Apr 2018 — Jun 2018 [monthly]

    Recruiting PHASE3

  31. Feb 2018 — Apr 2018 [monthly]

    Recruiting PHASE3

  32. Nov 2017 — Feb 2018 [monthly]

    Recruiting PHASE3

  33. Oct 2017 — Nov 2017 [monthly]

    Recruiting PHASE3

  34. Sep 2017 — Oct 2017 [monthly]

    Recruiting PHASE3

  35. Aug 2017 — Sep 2017 [monthly]

    Recruiting PHASE3

  36. Jun 2017 — Aug 2017 [monthly]

    Recruiting PHASE3

  37. May 2017 — Jun 2017 [monthly]

    Recruiting PHASE3

  38. Mar 2017 — May 2017 [monthly]

    Recruiting PHASE3

  39. Feb 2017 — Mar 2017 [monthly]

    Recruiting PHASE3

  40. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE3

    First recorded

Oct 2015

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • AstraZeneca
Data source: AstraZeneca

For direct contact, visit the study record on ClinicalTrials.gov .