deltatrials
Unknown NA INTERVENTIONAL 2-arm NCT02513797

aMAZE Study: LAA Ligation Adjunctive to PVI for Persistent or Longstanding Persistent Atrial Fibrillation (aMAZE)

Left Atrial Appendage Ligation With the LARIAT™ Suture Delivery System as Adjunctive Therapy to Pulmonary Vein Isolation for Persistent or Longstanding Persistent Atrial Fibrillation

Sponsor: AtriCure, Inc.

Conditions Atrial Fibrillation
Interventions LARIAT + PVI Pulmonary Vein Isolation
Updated 30 times since 2017 Last updated: Sep 2, 2021 Started: Sep 30, 2015 Primary completion: Apr 21, 2021 Completion: Mar 31, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A NA clinical study on Atrial Fibrillation, this trial is ongoing. The trial is conducted by AtriCure, Inc. and has accumulated 30 data snapshots since 2015. Cardiovascular trials of this type often inform treatment guidelines for long-term patient management.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Apr 2017 · 59 days · monthly snapshot~Apr 2017 – ~Jun 2017 · 2 months · monthly snapshot~Jun 2017 – ~Aug 2017 · 2 months · monthly snapshot~Aug 2017 – ~Oct 2017 · 2 months · monthly snapshot~Oct 2017 – ~Dec 2017 · 2 months · monthly snapshot~Dec 2017 – ~Mar 2018 · 3 months · monthly snapshot~Mar 2018 – ~Jun 2018 · 3 months · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Aug 2018 · 31 days · monthly snapshot~Aug 2018 – ~Jan 2019 · 5 months · monthly snapshot~Jan 2019 – ~Mar 2019 · 59 days · monthly snapshot~Mar 2019 – ~Apr 2019 · 31 days · monthly snapshot~Apr 2019 – ~May 2019 · 30 days · monthly snapshot~May 2019 – ~Jun 2019 · 31 days · monthly snapshot~Jun 2019 – ~Oct 2019 · 4 months · monthly snapshot~Oct 2019 – ~Dec 2019 · 2 months · monthly snapshot~Dec 2019 – ~Feb 2020 · 2 months · monthly snapshot~Feb 2020 – ~Mar 2020 · 29 days · monthly snapshot~Mar 2020 – ~Aug 2020 · 5 months · monthly snapshot~Aug 2020 – ~Oct 2020 · 2 months · monthly snapshot~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Oct 2023 · 24 months · monthly snapshot~Oct 2023 – ~Jul 2024 · 9 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

30 versions recorded

  1. Sep 2025 — Present [monthly]

    Unknown NA

  2. Sep 2024 — Sep 2025 [monthly]

    Unknown NA

  3. Jul 2024 — Sep 2024 [monthly]

    Unknown NA

    Status: Unknown Status → Unknown

  4. Oct 2023 — Jul 2024 [monthly]

    Unknown Status NA

    Status: Active Not Recruiting → Unknown Status

  5. Oct 2021 — Oct 2023 [monthly]

    Active Not Recruiting NA

▶ Show 25 earlier versions

  1. Sep 2021 — Oct 2021 [monthly]

    Active Not Recruiting NA

  2. Jan 2021 — Sep 2021 [monthly]

    Active Not Recruiting NA

  3. Nov 2020 — Jan 2021 [monthly]

    Active Not Recruiting NA

  4. Oct 2020 — Nov 2020 [monthly]

    Active Not Recruiting NA

  5. Aug 2020 — Oct 2020 [monthly]

    Active Not Recruiting NA

  6. Mar 2020 — Aug 2020 [monthly]

    Active Not Recruiting NA

    Status: Recruiting → Active Not Recruiting

  7. Feb 2020 — Mar 2020 [monthly]

    Recruiting NA

  8. Dec 2019 — Feb 2020 [monthly]

    Recruiting NA

  9. Oct 2019 — Dec 2019 [monthly]

    Recruiting NA

  10. Jun 2019 — Oct 2019 [monthly]

    Recruiting NA

  11. May 2019 — Jun 2019 [monthly]

    Recruiting NA

  12. Apr 2019 — May 2019 [monthly]

    Recruiting NA

  13. Mar 2019 — Apr 2019 [monthly]

    Recruiting NA

  14. Jan 2019 — Mar 2019 [monthly]

    Recruiting NA

  15. Aug 2018 — Jan 2019 [monthly]

    Recruiting NA

  16. Jul 2018 — Aug 2018 [monthly]

    Recruiting NA

  17. Jun 2018 — Jul 2018 [monthly]

    Recruiting NA

  18. Mar 2018 — Jun 2018 [monthly]

    Recruiting NA

  19. Dec 2017 — Mar 2018 [monthly]

    Recruiting NA

  20. Oct 2017 — Dec 2017 [monthly]

    Recruiting NA

  21. Aug 2017 — Oct 2017 [monthly]

    Recruiting NA

  22. Jun 2017 — Aug 2017 [monthly]

    Recruiting NA

  23. Apr 2017 — Jun 2017 [monthly]

    Recruiting NA

  24. Feb 2017 — Apr 2017 [monthly]

    Recruiting NA

  25. Jan 2017 — Feb 2017 [monthly]

    Recruiting NA

    First recorded

Sep 2015

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • AtriCure, Inc.
Data source: AtriCure, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Albuquerque, United States , Athens, United States , Atlanta, United States , Austin, United States , Baltimore, United States , Brooklyn, United States , Bryn Mawr, United States , Charleston, United States , Chicago, United States , Columbus, United States and 36 more locations