deltatrials
Completed PHASE1 INTERVENTIONAL 1-arm NCT02514668

A Study to Evaluate the Safety, Pharmacokinetics, and Efficacy of Isatuximab in Patients With Multiple Myeloma

An Open-label, Dose-escalation and Multi-center Study to Evaluate the Safety, Pharmacokinetics and Efficacy of SAR650984 (Isatuximab) in Patients With Relapsed/Refractory Multiple Myeloma

Sponsor: Sanofi

Conditions Plasma Cell Myeloma
Interventions Isatuximab
Updated 36 times since 2017 Last updated: Apr 22, 2022 Started: Sep 1, 2015 Primary completion: Dec 2, 2021 Completion: Dec 2, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT02514668, this PHASE1 trial focuses on Plasma Cell Myeloma and remains completed. Sponsored by Sanofi, it has been updated 36 times since 2015, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Mar 2017 · 28 days · monthly snapshot~Mar 2017 – ~Apr 2017 · 31 days · monthly snapshot~Apr 2017 – ~Jun 2017 · 2 months · monthly snapshot~Jun 2017 – ~Jul 2017 · 30 days · monthly snapshot~Jul 2017 – ~Oct 2017 · 3 months · monthly snapshot~Oct 2017 – ~Nov 2017 · 31 days · monthly snapshot~Nov 2017 – ~Dec 2017 · 30 days · monthly snapshot~Dec 2017 – ~Jan 2018 · 31 days · monthly snapshot~Jan 2018 – ~Apr 2018 · 3 months · monthly snapshot~Apr 2018 – ~Jun 2018 · 2 months · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Aug 2018 · 31 days · monthly snapshot~Aug 2018 – ~Sep 2018 · 31 days · monthly snapshot~Sep 2018 – ~Oct 2018 · 30 days · monthly snapshot~Oct 2018 – ~Feb 2019 · 4 months · monthly snapshot~Feb 2019 – ~Apr 2019 · 59 days · monthly snapshot~Apr 2019 – ~May 2019 · 30 days · monthly snapshot~May 2019 – ~Jun 2019 · 31 days · monthly snapshot~Jun 2019 – ~Jul 2019 · 30 days · monthly snapshot~Jul 2019 – ~Sep 2019 · 2 months · monthly snapshot~Sep 2019 – ~Oct 2019 · 30 days · monthly snapshot~Oct 2019 – ~Nov 2019 · 31 days · monthly snapshot~Nov 2019 – ~Dec 2019 · 30 days · monthly snapshot~Dec 2019 – ~Jan 2020 · 31 days · monthly snapshot~Jan 2020 – ~May 2020 · 4 months · monthly snapshot~May 2020 – ~Jul 2020 · 2 months · monthly snapshot~Jul 2020 – ~Jan 2021 · 6 months · monthly snapshot~Jan 2021 – ~Apr 2021 · 3 months · monthly snapshot~Apr 2021 – ~Oct 2021 · 6 months · monthly snapshot~Oct 2021 – ~Feb 2022 · 4 months · monthly snapshot~Feb 2022 – ~May 2022 · 3 months · monthly snapshot~May 2022 – ~Jul 2024 · 26 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

36 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed PHASE1

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  4. May 2022 — Jul 2024 [monthly]

    Completed PHASE1

  5. Feb 2022 — May 2022 [monthly]

    Completed PHASE1

    Status: Active Not Recruiting → Completed

▶ Show 31 earlier versions

  1. Oct 2021 — Feb 2022 [monthly]

    Active Not Recruiting PHASE1

  2. Apr 2021 — Oct 2021 [monthly]

    Active Not Recruiting PHASE1

  3. Jan 2021 — Apr 2021 [monthly]

    Active Not Recruiting PHASE1

  4. Jul 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE1

  5. May 2020 — Jul 2020 [monthly]

    Active Not Recruiting PHASE1

  6. Jan 2020 — May 2020 [monthly]

    Active Not Recruiting PHASE1

  7. Dec 2019 — Jan 2020 [monthly]

    Active Not Recruiting PHASE1

  8. Nov 2019 — Dec 2019 [monthly]

    Active Not Recruiting PHASE1

  9. Oct 2019 — Nov 2019 [monthly]

    Active Not Recruiting PHASE1

  10. Sep 2019 — Oct 2019 [monthly]

    Active Not Recruiting PHASE1

  11. Jul 2019 — Sep 2019 [monthly]

    Active Not Recruiting PHASE1

    Status: Recruiting → Active Not Recruiting

  12. Jun 2019 — Jul 2019 [monthly]

    Recruiting PHASE1

  13. May 2019 — Jun 2019 [monthly]

    Recruiting PHASE1

  14. Apr 2019 — May 2019 [monthly]

    Recruiting PHASE1

  15. Feb 2019 — Apr 2019 [monthly]

    Recruiting PHASE1

  16. Oct 2018 — Feb 2019 [monthly]

    Recruiting PHASE1

  17. Sep 2018 — Oct 2018 [monthly]

    Recruiting PHASE1

  18. Aug 2018 — Sep 2018 [monthly]

    Recruiting PHASE1

  19. Jul 2018 — Aug 2018 [monthly]

    Recruiting PHASE1

  20. Jun 2018 — Jul 2018 [monthly]

    Recruiting PHASE1

  21. Apr 2018 — Jun 2018 [monthly]

    Recruiting PHASE1

  22. Jan 2018 — Apr 2018 [monthly]

    Recruiting PHASE1

  23. Dec 2017 — Jan 2018 [monthly]

    Recruiting PHASE1

  24. Nov 2017 — Dec 2017 [monthly]

    Recruiting PHASE1

  25. Oct 2017 — Nov 2017 [monthly]

    Recruiting PHASE1

  26. Jul 2017 — Oct 2017 [monthly]

    Recruiting PHASE1

  27. Jun 2017 — Jul 2017 [monthly]

    Recruiting PHASE1

  28. Apr 2017 — Jun 2017 [monthly]

    Recruiting PHASE1

  29. Mar 2017 — Apr 2017 [monthly]

    Recruiting PHASE1

  30. Feb 2017 — Mar 2017 [monthly]

    Recruiting PHASE1

  31. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE1

    First recorded

Sep 2015

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Sanofi
Data source: Sanofi

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Brno, Czechia , Canton, United States , Créteil, France , Detroit, United States , Durham, United States , Hackensack, United States , Milwaukee, United States , Montpellier, France , Nantes, France , Nashville, United States and 8 more locations