deltatrials
Completed PHASE1 INTERVENTIONAL 3-arm NCT02549651

MEDI4736 Alone and in Combination With Tremelimumab or AZD9150 in Adult Subjects With Relapsed/Refractory DLBCL (D4190C00023)

A Phase 1b Study to Evaluate the Safety and Efficacy of MEDI4736 as Monotherapy and in Combination With Tremelimumab or AZD9150 in Subjects With Relapsed or Refractory Diffuse Large B-cell Lymphoma.

Sponsor: MedImmune LLC

Updated 19 times since 2017 Last updated: Feb 26, 2019 Started: Jul 13, 2016 Primary completion: Feb 4, 2019 Completion: Feb 4, 2019
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT02549651, this PHASE1 trial focuses on Diffuse Large B-Cell Lymphoma and remains completed. Sponsored by MedImmune LLC, it has been updated 19 times since 2016, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~May 2017 · 3 months · monthly snapshot~May 2017 – ~Oct 2017 · 5 months · monthly snapshot~Oct 2017 – ~Dec 2017 · 2 months · monthly snapshot~Dec 2017 – ~Jan 2018 · 31 days · monthly snapshot~Jan 2018 – ~Apr 2018 · 3 months · monthly snapshot~Apr 2018 – ~Jun 2018 · 2 months · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Aug 2018 · 31 days · monthly snapshot~Aug 2018 – ~Sep 2018 · 31 days · monthly snapshot~Sep 2018 – ~Nov 2018 · 2 months · monthly snapshot~Nov 2018 – ~Dec 2018 · 30 days · monthly snapshot~Dec 2018 – ~Jan 2019 · 31 days · monthly snapshot~Jan 2019 – ~Mar 2019 · 59 days · monthly snapshot~Mar 2019 – ~Jan 2021 · 22 months · monthly snapshot~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 9 months · monthly snapshot

Change History

19 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE1

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  4. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE1

  5. Mar 2019 — Jan 2021 [monthly]

    Completed PHASE1

    Status: Active Not RecruitingCompleted

Show 14 earlier versions
  1. Jan 2019 — Mar 2019 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  2. Dec 2018 — Jan 2019 [monthly]

    Recruiting PHASE1

  3. Nov 2018 — Dec 2018 [monthly]

    Recruiting PHASE1

  4. Sep 2018 — Nov 2018 [monthly]

    Recruiting PHASE1

  5. Aug 2018 — Sep 2018 [monthly]

    Recruiting PHASE1

  6. Jul 2018 — Aug 2018 [monthly]

    Recruiting PHASE1

  7. Jun 2018 — Jul 2018 [monthly]

    Recruiting PHASE1

  8. Apr 2018 — Jun 2018 [monthly]

    Recruiting PHASE1

  9. Jan 2018 — Apr 2018 [monthly]

    Recruiting PHASE1

  10. Dec 2017 — Jan 2018 [monthly]

    Recruiting PHASE1

  11. Oct 2017 — Dec 2017 [monthly]

    Recruiting PHASE1

  12. May 2017 — Oct 2017 [monthly]

    Recruiting PHASE1

  13. Feb 2017 — May 2017 [monthly]

    Recruiting PHASE1

  14. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE1

    First recorded

Jul 2016

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • MedImmune LLC
Data source: MedImmune LLC

For direct contact, visit the study record on ClinicalTrials.gov .