deltatrials
Completed PHASE1/PHASE2 INTERVENTIONAL 2-arm NCT02570308

A Study of the Intra-Patient Escalation Dosing Regimen With IMCgp100 in Patients With Advanced Uveal Melanoma

A Phase I/II Open-label, Multi-center Study of the Safety and Efficacy of IMCgp100 Using the Intra-patient Escalation Dosing Regimen in Patients With Advanced Uveal Melanoma

Sponsor: Immunocore Ltd

Conditions Uveal Melanoma
Interventions IMCgp100
Updated 33 times since 2017 Last updated: Feb 21, 2023 Started: Feb 29, 2016 Primary completion: Mar 20, 2020 Completion: Oct 17, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1/PHASE2 clinical study on Uveal Melanoma, this trial is completed. The trial is conducted by Immunocore Ltd and has accumulated 33 data snapshots since 2016. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Mar 2017 · 28 days · monthly snapshot~Mar 2017 – ~Aug 2017 · 5 months · monthly snapshot~Aug 2017 – ~Nov 2017 · 3 months · monthly snapshot~Nov 2017 – ~Mar 2018 · 4 months · monthly snapshot~Mar 2018 – ~May 2018 · 2 months · monthly snapshot~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Aug 2018 · 31 days · monthly snapshot~Aug 2018 – ~Sep 2018 · 31 days · monthly snapshot~Sep 2018 – ~Oct 2018 · 30 days · monthly snapshot~Oct 2018 – ~Nov 2018 · 31 days · monthly snapshot~Nov 2018 – ~Dec 2018 · 30 days · monthly snapshot~Dec 2018 – ~Jan 2019 · 31 days · monthly snapshot~Jan 2019 – ~Feb 2019 · 31 days · monthly snapshot~Feb 2019 – ~Mar 2019 · 28 days · monthly snapshot~Mar 2019 – ~Jun 2019 · 3 months · monthly snapshot~Jun 2019 – ~Jul 2019 · 30 days · monthly snapshot~Jul 2019 – ~Aug 2019 · 31 days · monthly snapshot~Aug 2019 – ~May 2020 · 9 months · monthly snapshot~May 2020 – ~Nov 2020 · 6 months · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Mar 2021 · 28 days · monthly snapshot~Mar 2021 – ~May 2021 · 2 months · monthly snapshot~May 2021 – ~Oct 2021 · 5 months · monthly snapshot~Oct 2021 – ~Dec 2021 · 2 months · monthly snapshot~Dec 2021 – ~Apr 2022 · 4 months · monthly snapshot~Apr 2022 – ~Apr 2023 · 12 months · monthly snapshot~Apr 2023 – ~Jul 2024 · 15 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

33 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE1/PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE1/PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1/PHASE2

    Phase: PHASE1_PHASE2PHASE1/PHASE2

  4. Apr 2023 — Jul 2024 [monthly]

    Completed PHASE1_PHASE2

    Status: Active Not RecruitingCompleted

  5. Apr 2022 — Apr 2023 [monthly]

    Active Not Recruiting PHASE1_PHASE2

Show 28 earlier versions
  1. Dec 2021 — Apr 2022 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  2. Oct 2021 — Dec 2021 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  3. May 2021 — Oct 2021 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  4. Mar 2021 — May 2021 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  5. Feb 2021 — Mar 2021 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  6. Jan 2021 — Feb 2021 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  7. Nov 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  8. May 2020 — Nov 2020 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  9. Aug 2019 — May 2020 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  10. Jul 2019 — Aug 2019 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  11. Jun 2019 — Jul 2019 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  12. Mar 2019 — Jun 2019 [monthly]

    Active Not Recruiting PHASE1_PHASE2

    Status: RecruitingActive Not Recruiting

  13. Feb 2019 — Mar 2019 [monthly]

    Recruiting PHASE1_PHASE2

  14. Jan 2019 — Feb 2019 [monthly]

    Recruiting PHASE1_PHASE2

  15. Dec 2018 — Jan 2019 [monthly]

    Recruiting PHASE1_PHASE2

  16. Nov 2018 — Dec 2018 [monthly]

    Recruiting PHASE1_PHASE2

  17. Oct 2018 — Nov 2018 [monthly]

    Recruiting PHASE1_PHASE2

  18. Sep 2018 — Oct 2018 [monthly]

    Recruiting PHASE1_PHASE2

  19. Aug 2018 — Sep 2018 [monthly]

    Recruiting PHASE1_PHASE2

  20. Jul 2018 — Aug 2018 [monthly]

    Recruiting PHASE1_PHASE2

  21. Jun 2018 — Jul 2018 [monthly]

    Recruiting PHASE1_PHASE2

  22. May 2018 — Jun 2018 [monthly]

    Recruiting PHASE1_PHASE2

    Phase: PHASE1PHASE1_PHASE2

  23. Mar 2018 — May 2018 [monthly]

    Recruiting PHASE1

  24. Nov 2017 — Mar 2018 [monthly]

    Recruiting PHASE1

  25. Aug 2017 — Nov 2017 [monthly]

    Recruiting PHASE1

  26. Mar 2017 — Aug 2017 [monthly]

    Recruiting PHASE1

  27. Feb 2017 — Mar 2017 [monthly]

    Recruiting PHASE1

  28. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE1

    First recorded

Feb 2016

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Immunocore Ltd
Data source: Immunocore Ltd

For direct contact, visit the study record on ClinicalTrials.gov .