deltatrials
Recruiting PHASE3 INTERVENTIONAL 3-arm NCT05549297

Tebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM)

Phase 2/3 Randomized Study of Tebentafusp as Monotherapy and in Combination With Pembrolizumab Versus Investigator's Choice in HLA-A*02:01-positive Participants With Previously Treated Advanced Melanoma (TEBE-AM)

Sponsor: Immunocore Ltd

Updated 13 times since 2022 Last updated: Feb 23, 2026 Started: Dec 19, 2022 Primary completion: Mar 31, 2028 Completion: Jul 31, 2028
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT05549297, this PHASE3 trial focuses on Advanced Melanoma and remains actively recruiting participants. Sponsored by Immunocore Ltd, it has been updated 13 times since 2022, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Sep 2022 – ~Mar 2023 · 6 months · monthly snapshot~Mar 2023 – ~Apr 2023 · 31 days · monthly snapshot~Apr 2023 – ~Oct 2023 · 6 months · monthly snapshot~Oct 2023 – ~Mar 2024 · 5 months · monthly snapshot~Mar 2024 – ~Apr 2024 · 31 days · monthly snapshot~Apr 2024 – ~Jul 2024 · 3 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Dec 2024 · 3 months · monthly snapshot~Dec 2024 – ~May 2025 · 5 months · monthly snapshot~May 2025 – ~Aug 2025 · 3 months · monthly snapshot~Aug 2025 – ~Sep 2025 · 31 days · monthly snapshot~Sep 2025 – ~Feb 2026 · 5 months · monthly snapshot~Feb 2026 – present · 5 months · monthly snapshot

Change History

13 versions recorded
  1. Feb 2026 — Present [monthly]

    Recruiting PHASE3

  2. Sep 2025 — Feb 2026 [monthly]

    Recruiting PHASE3

  3. Aug 2025 — Sep 2025 [monthly]

    Recruiting PHASE3

  4. May 2025 — Aug 2025 [monthly]

    Recruiting PHASE3

  5. Dec 2024 — May 2025 [monthly]

    Recruiting PHASE3

    Phase: PHASE2/PHASE3PHASE3

Show 8 earlier versions
  1. Sep 2024 — Dec 2024 [monthly]

    Recruiting PHASE2/PHASE3

  2. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE2/PHASE3

    Phase: PHASE2_PHASE3PHASE2/PHASE3

  3. Apr 2024 — Jul 2024 [monthly]

    Recruiting PHASE2_PHASE3

  4. Mar 2024 — Apr 2024 [monthly]

    Recruiting PHASE2_PHASE3

  5. Oct 2023 — Mar 2024 [monthly]

    Recruiting PHASE2_PHASE3

  6. Apr 2023 — Oct 2023 [monthly]

    Recruiting PHASE2_PHASE3

  7. Mar 2023 — Apr 2023 [monthly]

    Recruiting PHASE2_PHASE3

    Status: Not Yet RecruitingRecruiting

  8. Sep 2022 — Mar 2023 [monthly]

    Not Yet Recruiting PHASE2_PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Immunocore Ltd
Data source: Immunocore Ltd

For direct contact, visit the study record on ClinicalTrials.gov .