Completed PHASE2 INTERVENTIONAL 2-arm NCT02576990

Study of Pembrolizumab (MK-3475) in Participants With Relapsed or Refractory Primary Mediastinal Large B-cell Lymphoma or Relapsed or Refractory Richter Syndrome (MK-3475-170/KEYNOTE-170)

A Phase II Study of Pembrolizumab (MK-3475) in Subjects With Relapsed or Refractory Primary Mediastinal Large B-cell Lymphoma (rrPMBCL) or Relapsed or Refractory Richter Syndrome (rrRS)

Sponsor: Merck Sharp & Dohme LLC

Conditions Mediastinal Large B-cell Lymphoma Richter Syndrome

Interventions Pembrolizumab

Updated 22 times since 2017 Last updated: Jul 25, 2023 Started: Dec 2, 2015 Primary completion: May 28, 2019 Completion: Oct 23, 2020

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT02576990, this PHASE2 trial focuses on Mediastinal Large B-cell Lymphoma and Richter Syndrome and remains completed. Sponsored by Merck Sharp & Dohme LLC, it has been updated 22 times since 2015, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

Change History

22 versions recorded

Sep 2024 — Present [monthly]

Completed PHASE2
Jul 2024 — Sep 2024 [monthly]

Completed PHASE2
Aug 2023 — Jul 2024 [monthly]

Completed PHASE2
Jun 2022 — Aug 2023 [monthly]

Completed PHASE2
Dec 2021 — Jun 2022 [monthly]

Completed PHASE2

▶ Show 17 earlier versions

Nov 2021 — Dec 2021 [monthly]

Completed PHASE2
Feb 2021 — Nov 2021 [monthly]

Completed PHASE2
Jan 2021 — Feb 2021 [monthly]

Completed PHASE2
Dec 2020 — Jan 2021 [monthly]

Completed PHASE2

Status: Active Not Recruiting → Completed
Sep 2020 — Dec 2020 [monthly]

Active Not Recruiting PHASE2
Jul 2020 — Sep 2020 [monthly]

Active Not Recruiting PHASE2
May 2020 — Jul 2020 [monthly]

Active Not Recruiting PHASE2
Mar 2020 — May 2020 [monthly]

Active Not Recruiting PHASE2
Dec 2019 — Mar 2020 [monthly]

Active Not Recruiting PHASE2
Aug 2019 — Dec 2019 [monthly]

Active Not Recruiting PHASE2
Jun 2018 — Aug 2019 [monthly]

Active Not Recruiting PHASE2
Jan 2018 — Jun 2018 [monthly]

Active Not Recruiting PHASE2
Dec 2017 — Jan 2018 [monthly]

Active Not Recruiting PHASE2

Status: Recruiting → Active Not Recruiting
Oct 2017 — Dec 2017 [monthly]

Recruiting PHASE2
May 2017 — Oct 2017 [monthly]

Recruiting PHASE2
Feb 2017 — May 2017 [monthly]

Recruiting PHASE2
Jan 2017 — Feb 2017 [monthly]

Recruiting PHASE2

First recorded

Dec 2015

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Merck Sharp & Dohme LLC

Data source: Merck Sharp & Dohme LLC

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

No location information available.