deltatrials
Terminated PHASE3 INTERVENTIONAL 2-arm NCT02606045

Minimize Menorrhagia in Women With Von Willebrand Disease (VWDMin)

Prospective, Randomized, Crossover Trial Comparing Recombinant Von Willebrand Factor (rVWF) vs. Tranexamic Acid (TA) to Minimize Menorrhagia in Women With Von Willebrand Disease: The VWD Minimize Study

Sponsor: Duke University

Updated 26 times since 2017 Last updated: Jun 27, 2024 Started: Feb 7, 2019 Primary completion: Apr 30, 2022 Completion: Aug 30, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

The study stopped early due to slow recruitment.

Listed as NCT02606045, this PHASE3 trial focuses on Von Willebrand Diseases and remains terminated or withdrawn. Sponsored by Duke University, it has been updated 26 times since 2019, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Jun 2017 · 4 months · monthly snapshot~Jun 2017 – ~Dec 2017 · 6 months · monthly snapshot~Dec 2017 – ~Jun 2018 · 6 months · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Nov 2018 · 4 months · monthly snapshot~Nov 2018 – ~Jan 2019 · 2 months · monthly snapshot~Jan 2019 – ~Feb 2019 · 31 days · monthly snapshot~Feb 2019 – ~Mar 2019 · 28 days · monthly snapshot~Mar 2019 – ~Apr 2019 · 31 days · monthly snapshot~Apr 2019 – ~May 2019 · 30 days · monthly snapshot~May 2019 – ~Jul 2019 · 2 months · monthly snapshot~Jul 2019 – ~Apr 2020 · 9 months · monthly snapshot~Apr 2020 – ~Jul 2020 · 3 months · monthly snapshot~Jul 2020 – ~Jan 2021 · 6 months · monthly snapshot~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshot~Sep 2021 – ~Apr 2022 · 7 months · monthly snapshot~Apr 2022 – ~Sep 2022 · 5 months · monthly snapshot~Sep 2022 – ~Feb 2023 · 5 months · monthly snapshot~Feb 2023 – ~Jul 2023 · 5 months · monthly snapshot~Jul 2023 – ~Mar 2024 · 8 months · monthly snapshot~Mar 2024 – ~Jul 2024 · 4 months · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

26 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE3

  3. Aug 2024 — Sep 2024 [monthly]

    Terminated PHASE3

  4. Jul 2024 — Aug 2024 [monthly]

    Terminated PHASE3

  5. Mar 2024 — Jul 2024 [monthly]

    Terminated PHASE3

    Status: Active Not RecruitingTerminated

Show 21 earlier versions
  1. Jul 2023 — Mar 2024 [monthly]

    Active Not Recruiting PHASE3

  2. Feb 2023 — Jul 2023 [monthly]

    Active Not Recruiting PHASE3

  3. Sep 2022 — Feb 2023 [monthly]

    Active Not Recruiting PHASE3

  4. Apr 2022 — Sep 2022 [monthly]

    Active Not Recruiting PHASE3

    Status: RecruitingActive Not Recruiting

  5. Sep 2021 — Apr 2022 [monthly]

    Recruiting PHASE3

  6. Jan 2021 — Sep 2021 [monthly]

    Recruiting PHASE3

  7. Jul 2020 — Jan 2021 [monthly]

    Recruiting PHASE3

  8. Apr 2020 — Jul 2020 [monthly]

    Recruiting PHASE3

  9. Jul 2019 — Apr 2020 [monthly]

    Recruiting PHASE3

  10. May 2019 — Jul 2019 [monthly]

    Recruiting PHASE3

  11. Apr 2019 — May 2019 [monthly]

    Recruiting PHASE3

  12. Mar 2019 — Apr 2019 [monthly]

    Recruiting PHASE3

    Status: Not Yet RecruitingRecruiting

  13. Feb 2019 — Mar 2019 [monthly]

    Not Yet Recruiting PHASE3

  14. Jan 2019 — Feb 2019 [monthly]

    Not Yet Recruiting PHASE3

  15. Nov 2018 — Jan 2019 [monthly]

    Not Yet Recruiting PHASE3

  16. Jul 2018 — Nov 2018 [monthly]

    Not Yet Recruiting PHASE3

  17. Jun 2018 — Jul 2018 [monthly]

    Not Yet Recruiting PHASE3

  18. Dec 2017 — Jun 2018 [monthly]

    Not Yet Recruiting PHASE3

  19. Jun 2017 — Dec 2017 [monthly]

    Not Yet Recruiting PHASE3

  20. Feb 2017 — Jun 2017 [monthly]

    Not Yet Recruiting PHASE3

  21. Jan 2017 — Feb 2017 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Duke University
  • Margaret Ragni
  • National Heart, Lung, and Blood Institute (NHLBI)
  • University of North Carolina
Data source: University of Pittsburgh

For direct contact, visit the study record on ClinicalTrials.gov .