deltatrials
Completed PHASE1 INTERVENTIONAL 1-arm NCT02700230

Vaccine Therapy in Treating Patients with Malignant Peripheral Nerve Sheath Tumor That is Recurrent or Cannot Be Removed by Surgery

Phase I Trial of Intratumoral Administration of a NIS-Expressing Derivative Manufactured from a Genetically Engineered Strain of Measles Virus in Patients with Unresectable or Recurrent Malignant Peripheral Nerve Sheath Tumor

Sponsor: Mayo Clinic

Updated 18 times since 2017 Last updated: Sep 26, 2024 Started: Mar 22, 2017 Primary completion: Apr 17, 2024 Completion: Apr 17, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT02700230, this PHASE1 trial focuses on Metastatic Malignant Peripheral Nerve Sheath Tumor and Neurofibromatosis Type 1 and remains completed. Sponsored by Mayo Clinic, it has been updated 18 times since 2017, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Jun 2017 · 4 months · monthly snapshot~Jun 2017 – ~Oct 2017 · 4 months · monthly snapshot~Oct 2017 – ~Mar 2018 · 5 months · monthly snapshot~Mar 2018 – ~Jun 2018 · 3 months · monthly snapshot~Jun 2018 – ~May 2019 · 11 months · monthly snapshot~May 2019 – ~Jun 2020 · 13 months · monthly snapshot~Jun 2020 – ~Jan 2021 · 7 months · monthly snapshot~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshot~Sep 2021 – ~Sep 2022 · 12 months · monthly snapshot~Sep 2022 – ~Apr 2023 · 7 months · monthly snapshot~Apr 2023 – ~Aug 2023 · 4 months · monthly snapshot~Aug 2023 – ~Feb 2024 · 6 months · monthly snapshot~Feb 2024 – ~Mar 2024 · 29 days · monthly snapshot~Mar 2024 – ~Jul 2024 · 4 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – present · 19 months · monthly snapshot

Change History

18 versions recorded
  1. Oct 2024 — Present [monthly]

    Completed PHASE1

    Status: RecruitingCompleted

  2. Sep 2024 — Oct 2024 [monthly]

    Recruiting PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE1

  4. Mar 2024 — Jul 2024 [monthly]

    Recruiting PHASE1

  5. Feb 2024 — Mar 2024 [monthly]

    Recruiting PHASE1

Show 13 earlier versions
  1. Aug 2023 — Feb 2024 [monthly]

    Recruiting PHASE1

  2. Apr 2023 — Aug 2023 [monthly]

    Recruiting PHASE1

  3. Sep 2022 — Apr 2023 [monthly]

    Recruiting PHASE1

  4. Sep 2021 — Sep 2022 [monthly]

    Recruiting PHASE1

  5. Jan 2021 — Sep 2021 [monthly]

    Recruiting PHASE1

  6. Jun 2020 — Jan 2021 [monthly]

    Recruiting PHASE1

  7. May 2019 — Jun 2020 [monthly]

    Recruiting PHASE1

  8. Jun 2018 — May 2019 [monthly]

    Recruiting PHASE1

  9. Mar 2018 — Jun 2018 [monthly]

    Recruiting PHASE1

    Status: SuspendedRecruiting

  10. Oct 2017 — Mar 2018 [monthly]

    Suspended PHASE1

    Status: RecruitingSuspended

  11. Jun 2017 — Oct 2017 [monthly]

    Recruiting PHASE1

  12. Feb 2017 — Jun 2017 [monthly]

    Recruiting PHASE1

  13. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Mayo Clinic
Data source: Mayo Clinic

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations