deltatrials
Completed PHASE2 INTERVENTIONAL 2-arm NCT02708186

Study Evaluating Nelotanserin for Treatment of REM Sleep Behavior Disorder in Subjects With Dementia (DLB or PDD)

A Phase 2, Double-blind, Randomized, Placebo-controlled Study of Nelotanserin Versus Placebo in Subjects With Dementia With Lewy Bodies (DLB) or Parkinson's Disease Dementia (PDD) Who Have REM Sleep Behavior Disorder (RBD)

Sponsor: Axovant Sciences Ltd.

Updated 15 times since 2017 Last updated: May 9, 2020 Started: Mar 31, 2016 Primary completion: May 31, 2018 Completion: May 31, 2018
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT02708186, this PHASE2 trial focuses on Dementia With Lewy Bodies and Parkinson's Disease Dementia and remains completed. Sponsored by Axovant Sciences Ltd., it has been updated 15 times since 2016, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Mar 2017 · 28 days · monthly snapshot~Mar 2017 – ~Aug 2017 · 5 months · monthly snapshot~Aug 2017 – ~Feb 2018 · 6 months · monthly snapshot~Feb 2018 – ~Mar 2018 · 28 days · monthly snapshot~Mar 2018 – ~Jun 2018 · 3 months · monthly snapshot~Jun 2018 – ~Nov 2018 · 5 months · monthly snapshot~Nov 2018 – ~Jun 2020 · 19 months · monthly snapshot~Jun 2020 – ~Dec 2020 · 6 months · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Dec 2022 · 23 months · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Jul 2024 · 18 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 22 months · monthly snapshot

Change History

15 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  3. Jan 2023 — Jul 2024 [monthly]

    Completed PHASE2

  4. Dec 2022 — Jan 2023 [monthly]

    Completed PHASE2

  5. Jan 2021 — Dec 2022 [monthly]

    Completed PHASE2

Show 10 earlier versions
  1. Dec 2020 — Jan 2021 [monthly]

    Completed PHASE2

  2. Jun 2020 — Dec 2020 [monthly]

    Completed PHASE2

  3. Nov 2018 — Jun 2020 [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

  4. Jun 2018 — Nov 2018 [monthly]

    Active Not Recruiting PHASE2

  5. Mar 2018 — Jun 2018 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  6. Feb 2018 — Mar 2018 [monthly]

    Recruiting PHASE2

  7. Aug 2017 — Feb 2018 [monthly]

    Recruiting PHASE2

  8. Mar 2017 — Aug 2017 [monthly]

    Recruiting PHASE2

  9. Feb 2017 — Mar 2017 [monthly]

    Recruiting PHASE2

  10. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE2

    First recorded

Mar 2016

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Axovant Sciences Ltd.
Data source: Sio Gene Therapies

For direct contact, visit the study record on ClinicalTrials.gov .