deltatrials
Completed PHASE3 INTERVENTIONAL 2-arm NCT02585934

Study Evaluating Intepirdine (RVT-101) in Subjects With Mild to Moderate Alzheimer's Disease on Donepezil: MINDSET Study

A Phase 3, Double-blind, Randomized Study of RVT-101 Versus Placebo When Added to Existing Stable Donepezil Treatment in Subjects With Mild to Moderate Alzheimer's Disease

Sponsor: Axovant Sciences Ltd.

Interventions Placebo RVT-101
Updated 14 times since 2017 Last updated: Nov 8, 2018 Started: Oct 31, 2015 Primary completion: Sep 30, 2017 Completion: Sep 30, 2017
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Alzheimer's Disease and is currently completed. Axovant Sciences Ltd. leads this study, which shows 14 recorded versions since 2015 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Mar 2017 · 28 days · monthly snapshot~Mar 2017 – ~Jul 2017 · 4 months · monthly snapshot~Jul 2017 – ~Aug 2017 · 31 days · monthly snapshot~Aug 2017 – ~Oct 2017 · 2 months · monthly snapshot~Oct 2017 – ~Feb 2018 · 4 months · monthly snapshot~Feb 2018 – ~Jun 2018 · 4 months · monthly snapshot~Jun 2018 – ~Jan 2019 · 7 months · monthly snapshot~Jan 2019 – ~Dec 2020 · 23 months · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 11 months · monthly snapshot

Change History

14 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  4. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE3

  5. Dec 2020 — Jan 2021 [monthly]

    Completed PHASE3

Show 9 earlier versions
  1. Jan 2019 — Dec 2020 [monthly]

    Completed PHASE3

  2. Jun 2018 — Jan 2019 [monthly]

    Completed PHASE3

  3. Feb 2018 — Jun 2018 [monthly]

    Completed PHASE3

  4. Oct 2017 — Feb 2018 [monthly]

    Completed PHASE3

    Status: Active Not RecruitingCompleted

  5. Aug 2017 — Oct 2017 [monthly]

    Active Not Recruiting PHASE3

  6. Jul 2017 — Aug 2017 [monthly]

    Active Not Recruiting PHASE3

  7. Mar 2017 — Jul 2017 [monthly]

    Active Not Recruiting PHASE3

  8. Feb 2017 — Mar 2017 [monthly]

    Active Not Recruiting PHASE3

    Status: RecruitingActive Not Recruiting

  9. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE3

    First recorded

Oct 2015

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Axovant Sciences Ltd.
Data source: Sio Gene Therapies

For direct contact, visit the study record on ClinicalTrials.gov .