deltatrials
Terminated PHASE4 INTERVENTIONAL 2-arm NCT02829424

Multicenter Randomized Double Blind Controlled-study to Assess the Potential of Methotrexate Versus Placebo to Improve and Maintain Response to Anti TNF- Alpha Agents in Adult Patients With Moderate to Severe Psoriasis (METHOBIO)

Sponsor: Assistance Publique Hopitaux De Marseille

Conditions Psoriasis
Updated 10 times since 2017 Last updated: Nov 17, 2025 Started: Jan 23, 2017 Primary completion: Jan 10, 2023 Completion: Feb 10, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

new treatment on the market in direct competition with the new treatment proposed by the study. Recruitment difficulties.

A PHASE4 clinical study on Psoriasis, this trial is terminated or withdrawn. The trial is conducted by Assistance Publique Hopitaux De Marseille and has accumulated 10 data snapshots since 2017. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Jan 2017 – ~Jun 2018 · 17 months · monthly snapshotRecruiting~Jun 2018 – ~Nov 2020 · 29 months · monthly snapshotRecruiting~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshotUnknown Status~Jan 2021 – ~Sep 2023 · 32 months · monthly snapshotUnknown Status~Sep 2023 – ~Jul 2024 · 10 months · monthly snapshotActive Not Recruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotActive Not Recruiting~Sep 2024 – ~Jun 2025 · 9 months · monthly snapshotActive Not Recruiting~Jun 2025 – ~Sep 2025 · 3 months · monthly snapshotTerminated~Sep 2025 – ~Dec 2025 · 3 months · monthly snapshotTerminated~Dec 2025 – present · 7 months · monthly snapshotTerminated

Change History

10 versions recorded
  1. Dec 2025 — Present [monthly]

    Terminated PHASE4

  2. Sep 2025 — Dec 2025 [monthly]

    Terminated PHASE4

  3. Jun 2025 — Sep 2025 [monthly]

    Terminated PHASE4

    Status: Active Not RecruitingTerminated

  4. Sep 2024 — Jun 2025 [monthly]

    Active Not Recruiting PHASE4

  5. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE4

Show 5 earlier versions
  1. Sep 2023 — Jul 2024 [monthly]

    Active Not Recruiting PHASE4

    Status: Unknown StatusActive Not Recruiting

  2. Jan 2021 — Sep 2023 [monthly]

    Unknown Status PHASE4

  3. Nov 2020 — Jan 2021 [monthly]

    Unknown Status PHASE4

    Status: RecruitingUnknown Status

  4. Jun 2018 — Nov 2020 [monthly]

    Recruiting PHASE4

  5. Jan 2017 — Jun 2018 [monthly]

    Recruiting PHASE4

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Assistance Publique Hopitaux De Marseille
Data source: Assistance Publique Hopitaux De Marseille

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations