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Completed PHASE2 INTERVENTIONAL 2-arm NCT02873195

Capecitabine and Bevacizumab With or Without Atezolizumab in Treating Patients With Refractory Metastatic Colorectal Cancer

BACCI: A Phase II Randomized, Double-Blind, Placebo-Controlled Study of Capecitabine Bevacizumab Plus Atezolizumab Versus Capecitabine Bevacizumab Plus Placebo in Patients With Refractory Metastatic Colorectal Cancer

Sponsor: Academic and Community Cancer Research United

Conditions Metastatic Colorectal Carcinoma Recurrent Colorectal Carcinoma Refractory Colorectal Carcinoma Stage IV Colorectal Cancer AJCC v7 Stage IVA Colorectal Cancer AJCC v7 Stage IVB Colorectal Cancer AJCC v7
Interventions Atezolizumab Bevacizumab Capecitabine Laboratory Biomarker Analysis Placebo
Updated 28 times since 2017 Last updated: Jul 30, 2024 Started: Jul 7, 2017 Primary completion: Mar 6, 2023 Completion: Dec 1, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT02873195, this PHASE2 trial focuses on Metastatic Colorectal Carcinoma and Recurrent Colorectal Carcinoma and remains completed. Sponsored by Academic and Community Cancer Research United, it has been updated 28 times since 2017, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Apr 2017 · 59 days · monthly snapshot~Apr 2017 – ~Nov 2017 · 7 months · monthly snapshot~Nov 2017 – ~Dec 2017 · 30 days · monthly snapshot~Dec 2017 – ~Jun 2018 · 6 months · monthly snapshot~Jun 2018 – ~Aug 2018 · 2 months · monthly snapshot~Aug 2018 – ~Feb 2019 · 6 months · monthly snapshot~Feb 2019 – ~May 2019 · 3 months · monthly snapshot~May 2019 – ~Jun 2019 · 31 days · monthly snapshot~Jun 2019 – ~Dec 2019 · 6 months · monthly snapshot~Dec 2019 – ~Feb 2020 · 2 months · monthly snapshot~Feb 2020 – ~Mar 2020 · 29 days · monthly snapshot~Mar 2020 – ~Aug 2020 · 5 months · monthly snapshot~Aug 2020 – ~Jan 2021 · 5 months · monthly snapshot~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~Jun 2021 · 3 months · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Feb 2022 · 5 months · monthly snapshot~Feb 2022 – ~Mar 2023 · 13 months · monthly snapshot~Mar 2023 – ~Jun 2023 · 3 months · monthly snapshot~Jun 2023 – ~Sep 2023 · 3 months · monthly snapshot~Sep 2023 – ~Oct 2023 · 30 days · monthly snapshot~Oct 2023 – ~Nov 2023 · 31 days · monthly snapshot~Nov 2023 – ~Jan 2024 · 2 months · monthly snapshot~Jan 2024 – ~Jun 2024 · 5 months · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 22 months · monthly snapshot

Change History

28 versions recorded

  1. Sep 2024 — Present [monthly]

    Completed PHASE2

    Status: Active Not Recruiting → Completed

  2. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE2

  3. Jun 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE2

  4. Jan 2024 — Jun 2024 [monthly]

    Active Not Recruiting PHASE2

  5. Nov 2023 — Jan 2024 [monthly]

    Active Not Recruiting PHASE2

▶ Show 23 earlier versions

  1. Oct 2023 — Nov 2023 [monthly]

    Active Not Recruiting PHASE2

  2. Sep 2023 — Oct 2023 [monthly]

    Active Not Recruiting PHASE2

  3. Jun 2023 — Sep 2023 [monthly]

    Active Not Recruiting PHASE2

  4. Mar 2023 — Jun 2023 [monthly]

    Active Not Recruiting PHASE2

  5. Feb 2022 — Mar 2023 [monthly]

    Active Not Recruiting PHASE2

  6. Sep 2021 — Feb 2022 [monthly]

    Active Not Recruiting PHASE2

  7. Jun 2021 — Sep 2021 [monthly]

    Active Not Recruiting PHASE2

  8. Mar 2021 — Jun 2021 [monthly]

    Active Not Recruiting PHASE2

  9. Jan 2021 — Mar 2021 [monthly]

    Active Not Recruiting PHASE2

  10. Aug 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE2

  11. Mar 2020 — Aug 2020 [monthly]

    Active Not Recruiting PHASE2

  12. Feb 2020 — Mar 2020 [monthly]

    Active Not Recruiting PHASE2

  13. Dec 2019 — Feb 2020 [monthly]

    Active Not Recruiting PHASE2

  14. Jun 2019 — Dec 2019 [monthly]

    Active Not Recruiting PHASE2

  15. May 2019 — Jun 2019 [monthly]

    Active Not Recruiting PHASE2

  16. Feb 2019 — May 2019 [monthly]

    Active Not Recruiting PHASE2

  17. Aug 2018 — Feb 2019 [monthly]

    Active Not Recruiting PHASE2

    Status: Recruiting → Active Not Recruiting

  18. Jun 2018 — Aug 2018 [monthly]

    Recruiting PHASE2

  19. Dec 2017 — Jun 2018 [monthly]

    Recruiting PHASE2

  20. Nov 2017 — Dec 2017 [monthly]

    Recruiting PHASE2

    Status: Not Yet Recruiting → Recruiting

  21. Apr 2017 — Nov 2017 [monthly]

    Not Yet Recruiting PHASE2

  22. Feb 2017 — Apr 2017 [monthly]

    Not Yet Recruiting PHASE2

  23. Jan 2017 — Feb 2017 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Academic and Community Cancer Research United
  • National Cancer Institute (NCI)
Data source: Academic and Community Cancer Research United

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations