deltatrials
Completed PHASE4 INTERVENTIONAL 2-arm NCT02959983

Efficacy of Eluxadoline in the Treatment of Irritable Bowel Syndrome With Diarrhea in Patients With Inadequate Control of Symptoms With Prior Loperamide Use

A Phase 4 Multicenter, Multinational, Prospective, Randomized, Placebo-Controlled, Double-Blinded Parallel Group Study to Assess Efficacy of Eluxadoline in the Treatment of Irritable Bowel Syndrome With Diarrhea (IBS-D) in Patients Who Report Inadequate Control of IBS-D Symptoms With Prior Loperamide Use (RELIEF)

Sponsor: Allergan

Updated 12 times since 2017 Last updated: Jan 22, 2019 Started: Oct 25, 2016 Primary completion: Jan 22, 2018 Completion: Jan 22, 2018
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE4 trial investigates Irritable Bowel Syndrome With Diarrhea and is currently completed. Allergan leads this study, which shows 12 recorded versions since 2016 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotRecruiting~Feb 2017 – ~Mar 2017 · 28 days · monthly snapshotRecruiting~Mar 2017 – ~Jun 2017 · 3 months · monthly snapshotRecruiting~Jun 2017 – ~Aug 2017 · 2 months · monthly snapshotRecruiting~Aug 2017 – ~Mar 2018 · 7 months · monthly snapshotRecruiting~Mar 2018 – ~Jun 2018 · 3 months · monthly snapshotCompleted~Jun 2018 – ~Mar 2019 · 9 months · monthly snapshotCompleted~Mar 2019 – ~Jan 2021 · 22 months · monthly snapshotCompleted~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 9 months · monthly snapshotCompleted

Change History

12 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE4

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE4

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE4

  4. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE4

  5. Mar 2019 — Jan 2021 [monthly]

    Completed PHASE4

Show 7 earlier versions
  1. Jun 2018 — Mar 2019 [monthly]

    Completed PHASE4

  2. Mar 2018 — Jun 2018 [monthly]

    Completed PHASE4

    Status: RecruitingCompleted

  3. Aug 2017 — Mar 2018 [monthly]

    Recruiting PHASE4

  4. Jun 2017 — Aug 2017 [monthly]

    Recruiting PHASE4

  5. Mar 2017 — Jun 2017 [monthly]

    Recruiting PHASE4

  6. Feb 2017 — Mar 2017 [monthly]

    Recruiting PHASE4

  7. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE4

    First recorded

Oct 2016

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Allergan
Data source: Allergan

For direct contact, visit the study record on ClinicalTrials.gov .