deltatrials
Completed PHASE1 INTERVENTIONAL 1-arm NCT03009201

Ribociclib and Doxorubicin in Treating Patients With Metastatic or Advanced Soft Tissue Sarcomas That Cannot Be Removed by Surgery

A Phase 1B Study of Ribociclib in Combination With Doxorubicin in Advanced Soft Tissue Sarcomas

Sponsor: Novartis Pharmaceuticals

Updated 15 times since 2017 Last updated: Aug 14, 2023 Started: Mar 10, 2017 Primary completion: Oct 8, 2019 Completion: Jun 30, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1 trial investigates Advanced Soft Tissue Sarcoma and Locally Advanced Angiosarcoma and is currently completed. Novartis Pharmaceuticals leads this study, which shows 15 recorded versions since 2017 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~May 2017 · 3 months · monthly snapshot~May 2017 – ~Jun 2018 · 13 months · monthly snapshot~Jun 2018 – ~Apr 2019 · 10 months · monthly snapshot~Apr 2019 – ~Jan 2020 · 9 months · monthly snapshot~Jan 2020 – ~Jul 2020 · 6 months · monthly snapshot~Jul 2020 – ~Jan 2021 · 6 months · monthly snapshot~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshot~Sep 2021 – ~Jan 2022 · 4 months · monthly snapshot~Jan 2022 – ~Jul 2022 · 6 months · monthly snapshot~Jul 2022 – ~Feb 2023 · 7 months · monthly snapshot~Feb 2023 – ~Sep 2023 · 7 months · monthly snapshot~Sep 2023 – ~Jul 2024 · 10 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 22 months · monthly snapshot

Change History

15 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  3. Sep 2023 — Jul 2024 [monthly]

    Completed PHASE1

    Status: Active Not RecruitingCompleted

  4. Feb 2023 — Sep 2023 [monthly]

    Active Not Recruiting PHASE1

  5. Jul 2022 — Feb 2023 [monthly]

    Active Not Recruiting PHASE1

Show 10 earlier versions
  1. Jan 2022 — Jul 2022 [monthly]

    Active Not Recruiting PHASE1

  2. Sep 2021 — Jan 2022 [monthly]

    Active Not Recruiting PHASE1

  3. Jan 2021 — Sep 2021 [monthly]

    Active Not Recruiting PHASE1

  4. Jul 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE1

  5. Jan 2020 — Jul 2020 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  6. Apr 2019 — Jan 2020 [monthly]

    Recruiting PHASE1

  7. Jun 2018 — Apr 2019 [monthly]

    Recruiting PHASE1

  8. May 2017 — Jun 2018 [monthly]

    Recruiting PHASE1

    Status: Not Yet RecruitingRecruiting

  9. Feb 2017 — May 2017 [monthly]

    Not Yet Recruiting PHASE1

  10. Jan 2017 — Feb 2017 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Novartis Pharmaceuticals
  • OHSU Knight Cancer Institute
  • Oregon Health and Science University
Data source: OHSU Knight Cancer Institute

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations