deltatrials
Not Yet Recruiting PHASE1/PHASE2 INTERVENTIONAL 2-arm NCT03038802

A Randomised Controlled Phase 1 Study of Vaccine Therapy for Control or Cure of Chronic Hepatitis B Virus Infection (HBV003)

Sponsor: Australian Respiratory and Sleep Medicine Institute

Conditions Chronic Hepatitis b
Interventions Commercial Hepatitis B vaccine Therapeutic hepatitis B vaccine
Updated 13 times since 2017 Last updated: Sep 16, 2025 Started: Mar 1, 2026 Primary completion: Mar 1, 2027 Completion: Jun 30, 2027
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1/PHASE2 trial investigates Chronic Hepatitis b and is currently actively recruiting participants. Australian Respiratory and Sleep Medicine Institute leads this study, which shows 13 recorded versions since 2026 — indicating substantial longitudinal coverage. Longitudinal tracking of infectious disease trials helps identify durability of treatment effects.

Status Flow

~Feb 2017 – ~Jun 2018 · 16 months · monthly snapshot~Jun 2018 – ~Nov 2018 · 5 months · monthly snapshot~Nov 2018 – ~Jun 2019 · 7 months · monthly snapshot~Jun 2019 – ~Jul 2020 · 13 months · monthly snapshot~Jul 2020 – ~Jan 2021 · 6 months · monthly snapshot~Jan 2021 – ~May 2021 · 4 months · monthly snapshot~May 2021 – ~Apr 2022 · 11 months · monthly snapshot~Apr 2022 – ~Apr 2023 · 12 months · monthly snapshot~Apr 2023 – ~May 2024 · 13 months · monthly snapshot~May 2024 – ~Jul 2024 · 2 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Oct 2025 · 13 months · monthly snapshot~Oct 2025 – present · 11 months · monthly snapshot

Change History

13 versions recorded

  1. Oct 2025 — Present [monthly]

    Not Yet Recruiting PHASE1/PHASE2

  2. Sep 2024 — Oct 2025 [monthly]

    Not Yet Recruiting PHASE1/PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Not Yet Recruiting PHASE1/PHASE2

    Phase: PHASE1_PHASE2 → PHASE1/PHASE2

  4. May 2024 — Jul 2024 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

  5. Apr 2023 — May 2024 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

▶ Show 8 earlier versions

  1. Apr 2022 — Apr 2023 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

  2. May 2021 — Apr 2022 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

  3. Jan 2021 — May 2021 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

  4. Jul 2020 — Jan 2021 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

  5. Jun 2019 — Jul 2020 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

  6. Nov 2018 — Jun 2019 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

  7. Jun 2018 — Nov 2018 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

  8. Feb 2017 — Jun 2018 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Australian Respiratory and Sleep Medicine Institute
  • Vaxine Pty Ltd
Data source: Vaxine Pty Ltd

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations