deltatrials
Completed PHASE3 INTERVENTIONAL 2-arm NCT03057951

EMPagliflozin outcomE tRial in Patients With chrOnic heaRt Failure With Preserved Ejection Fraction (EMPEROR-Preserved)

A Phase III Randomised, Double-blind Trial to Evaluate Efficacy and Safety of Once Daily Empagliflozin 10 mg Compared to Placebo, in Patients With Chronic Heart Failure With Preserved Ejection Fraction (HFpEF)

Sponsor: Boehringer Ingelheim

Conditions Heart Failure
Interventions Empagliflozin Placebo
Updated 58 times since 2017 Last updated: Jun 3, 2022 Started: Mar 2, 2017 Primary completion: Apr 26, 2021 Completion: Apr 26, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Heart Failure and is currently completed. Boehringer Ingelheim leads this study, which shows 58 recorded versions since 2017 — indicating substantial longitudinal coverage. Heart and vascular conditions benefit from the kind of long-term tracking this trial provides.

Status Flow

~Mar 2017 – ~Apr 2017 · 31 days · monthly snapshot~Apr 2017 – ~May 2017 · 30 days · monthly snapshot~May 2017 – ~Jun 2017 · 31 days · monthly snapshot~Jun 2017 – ~Jul 2017 · 30 days · monthly snapshot~Jul 2017 – ~Aug 2017 · 31 days · monthly snapshot~Aug 2017 – ~Oct 2017 · 2 months · monthly snapshot~Oct 2017 – ~Nov 2017 · 31 days · monthly snapshot~Nov 2017 – ~Dec 2017 · 30 days · monthly snapshot~Dec 2017 – ~Jan 2018 · 31 days · monthly snapshot~Jan 2018 – ~Feb 2018 · 31 days · monthly snapshot~Feb 2018 – ~Mar 2018 · 28 days · monthly snapshot~Mar 2018 – ~Apr 2018 · 31 days · monthly snapshot~Apr 2018 – ~May 2018 · 30 days · monthly snapshot~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Aug 2018 · 31 days · monthly snapshot~Aug 2018 – ~Sep 2018 · 31 days · monthly snapshot~Sep 2018 – ~Oct 2018 · 30 days · monthly snapshot~Oct 2018 – ~Nov 2018 · 31 days · monthly snapshot~Nov 2018 – ~Dec 2018 · 30 days · monthly snapshot~Dec 2018 – ~Jan 2019 · 31 days · monthly snapshot~Jan 2019 – ~Feb 2019 · 31 days · monthly snapshot~Feb 2019 – ~Mar 2019 · 28 days · monthly snapshot~Mar 2019 – ~Apr 2019 · 31 days · monthly snapshot~Apr 2019 – ~May 2019 · 30 days · monthly snapshot~May 2019 – ~Jun 2019 · 31 days · monthly snapshot~Jun 2019 – ~Jul 2019 · 30 days · monthly snapshot~Jul 2019 – ~Aug 2019 · 31 days · monthly snapshot~Aug 2019 – ~Sep 2019 · 31 days · monthly snapshot~Sep 2019 – ~Oct 2019 · 30 days · monthly snapshot~Oct 2019 – ~Nov 2019 · 31 days · monthly snapshot~Nov 2019 – ~Dec 2019 · 30 days · monthly snapshot~Dec 2019 – ~Jan 2020 · 31 days · monthly snapshot~Jan 2020 – ~Feb 2020 · 31 days · monthly snapshot~Feb 2020 – ~Mar 2020 · 29 days · monthly snapshot~Mar 2020 – ~Apr 2020 · 31 days · monthly snapshot~Apr 2020 – ~May 2020 · 30 days · monthly snapshot~May 2020 – ~Jun 2020 · 31 days · monthly snapshot~Jun 2020 – ~Jul 2020 · 30 days · monthly snapshot~Jul 2020 – ~Aug 2020 · 31 days · monthly snapshot~Aug 2020 – ~Sep 2020 · 31 days · monthly snapshot~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshot~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Dec 2020 · 30 days · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Mar 2021 · 28 days · monthly snapshot~Mar 2021 – ~Apr 2021 · 31 days · monthly snapshot~Apr 2021 – ~May 2021 · 30 days · monthly snapshot~May 2021 – ~Jun 2021 · 31 days · monthly snapshot~Jun 2021 – ~Jul 2022 · 13 months · monthly snapshot~Jul 2022 – ~Jul 2024 · 24 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – ~Oct 2025 · 30 days · monthly snapshot~Oct 2025 – ~Nov 2025 · 31 days · monthly snapshot~Nov 2025 – ~Feb 2026 · 3 months · monthly snapshot~Feb 2026 – present · 7 months · monthly snapshot

Change History

58 versions recorded

  1. Feb 2026 — Present [monthly]

    Completed PHASE3

  2. Nov 2025 — Feb 2026 [monthly]

    Completed PHASE3

  3. Oct 2025 — Nov 2025 [monthly]

    Completed PHASE3

  4. Sep 2025 — Oct 2025 [monthly]

    Completed PHASE3

  5. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

▶ Show 53 earlier versions

  1. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  2. Jul 2022 — Jul 2024 [monthly]

    Completed PHASE3

  3. Jun 2021 — Jul 2022 [monthly]

    Completed PHASE3

    Status: Active Not Recruiting → Completed

  4. May 2021 — Jun 2021 [monthly]

    Active Not Recruiting PHASE3

  5. Apr 2021 — May 2021 [monthly]

    Active Not Recruiting PHASE3

  6. Mar 2021 — Apr 2021 [monthly]

    Active Not Recruiting PHASE3

  7. Feb 2021 — Mar 2021 [monthly]

    Active Not Recruiting PHASE3

  8. Jan 2021 — Feb 2021 [monthly]

    Active Not Recruiting PHASE3

  9. Dec 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE3

  10. Nov 2020 — Dec 2020 [monthly]

    Active Not Recruiting PHASE3

  11. Oct 2020 — Nov 2020 [monthly]

    Active Not Recruiting PHASE3

  12. Sep 2020 — Oct 2020 [monthly]

    Active Not Recruiting PHASE3

  13. Aug 2020 — Sep 2020 [monthly]

    Active Not Recruiting PHASE3

  14. Jul 2020 — Aug 2020 [monthly]

    Active Not Recruiting PHASE3

  15. Jun 2020 — Jul 2020 [monthly]

    Active Not Recruiting PHASE3

  16. May 2020 — Jun 2020 [monthly]

    Active Not Recruiting PHASE3

    Status: Recruiting → Active Not Recruiting

  17. Apr 2020 — May 2020 [monthly]

    Recruiting PHASE3

  18. Mar 2020 — Apr 2020 [monthly]

    Recruiting PHASE3

  19. Feb 2020 — Mar 2020 [monthly]

    Recruiting PHASE3

  20. Jan 2020 — Feb 2020 [monthly]

    Recruiting PHASE3

  21. Dec 2019 — Jan 2020 [monthly]

    Recruiting PHASE3

  22. Nov 2019 — Dec 2019 [monthly]

    Recruiting PHASE3

  23. Oct 2019 — Nov 2019 [monthly]

    Recruiting PHASE3

  24. Sep 2019 — Oct 2019 [monthly]

    Recruiting PHASE3

  25. Aug 2019 — Sep 2019 [monthly]

    Recruiting PHASE3

  26. Jul 2019 — Aug 2019 [monthly]

    Recruiting PHASE3

  27. Jun 2019 — Jul 2019 [monthly]

    Recruiting PHASE3

  28. May 2019 — Jun 2019 [monthly]

    Recruiting PHASE3

  29. Apr 2019 — May 2019 [monthly]

    Recruiting PHASE3

  30. Mar 2019 — Apr 2019 [monthly]

    Recruiting PHASE3

  31. Feb 2019 — Mar 2019 [monthly]

    Recruiting PHASE3

  32. Jan 2019 — Feb 2019 [monthly]

    Recruiting PHASE3

  33. Dec 2018 — Jan 2019 [monthly]

    Recruiting PHASE3

  34. Nov 2018 — Dec 2018 [monthly]

    Recruiting PHASE3

  35. Oct 2018 — Nov 2018 [monthly]

    Recruiting PHASE3

  36. Sep 2018 — Oct 2018 [monthly]

    Recruiting PHASE3

  37. Aug 2018 — Sep 2018 [monthly]

    Recruiting PHASE3

  38. Jul 2018 — Aug 2018 [monthly]

    Recruiting PHASE3

  39. Jun 2018 — Jul 2018 [monthly]

    Recruiting PHASE3

  40. May 2018 — Jun 2018 [monthly]

    Recruiting PHASE3

  41. Apr 2018 — May 2018 [monthly]

    Recruiting PHASE3

  42. Mar 2018 — Apr 2018 [monthly]

    Recruiting PHASE3

  43. Feb 2018 — Mar 2018 [monthly]

    Recruiting PHASE3

  44. Jan 2018 — Feb 2018 [monthly]

    Recruiting PHASE3

  45. Dec 2017 — Jan 2018 [monthly]

    Recruiting PHASE3

  46. Nov 2017 — Dec 2017 [monthly]

    Recruiting PHASE3

  47. Oct 2017 — Nov 2017 [monthly]

    Recruiting PHASE3

  48. Aug 2017 — Oct 2017 [monthly]

    Recruiting PHASE3

  49. Jul 2017 — Aug 2017 [monthly]

    Recruiting PHASE3

  50. Jun 2017 — Jul 2017 [monthly]

    Recruiting PHASE3

  51. May 2017 — Jun 2017 [monthly]

    Recruiting PHASE3

    Status: Not Yet Recruiting → Recruiting

  52. Apr 2017 — May 2017 [monthly]

    Not Yet Recruiting PHASE3

  53. Mar 2017 — Apr 2017 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Boehringer Ingelheim
  • Eli Lilly and Company
Data source: Boehringer Ingelheim

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Aachen, Germany , Adelaide, Australia , Aguascalientes, Mexico , Ahmedabad, India , Aichi, Kasugai, Japan , Aichi, Nagoya, Japan , Albany, United States , Alberton, South Africa , Almelo, Netherlands , Alpena, United States and 458 more locations