EMPagliflozin outcomE tRial in Patients With chrOnic heaRt Failure With Reduced Ejection Fraction (EMPEROR-Reduced)
A Phase III Randomised, Double-blind Trial to Evaluate Efficacy and Safety of Once Daily Empagliflozin 10 mg Compared to Placebo, in Patients With Chronic Heart Failure With Reduced Ejection Fraction (HFrEF)
Sponsor: Boehringer Ingelheim
Listed as NCT03057977, this PHASE3 trial focuses on Heart Failure and remains completed. Sponsored by Boehringer Ingelheim, it has been updated 49 times since 2017, reflecting substantial change activity. This study contributes longitudinal data to the cardiovascular research landscape.
Status Flow
Change History
49 versions recorded-
Mar 2026 — Present [monthly]
Completed PHASE3
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Feb 2026 — Mar 2026 [monthly]
Completed PHASE3
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Nov 2025 — Feb 2026 [monthly]
Completed PHASE3
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Oct 2025 — Nov 2025 [monthly]
Completed PHASE3
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Sep 2025 — Oct 2025 [monthly]
Completed PHASE3
▶ Show 44 earlier versions
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Sep 2024 — Sep 2025 [monthly]
Completed PHASE3
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Jul 2024 — Sep 2024 [monthly]
Completed PHASE3
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Jun 2021 — Jul 2024 [monthly]
Completed PHASE3
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Jan 2021 — Jun 2021 [monthly]
Completed PHASE3
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Sep 2020 — Jan 2021 [monthly]
Completed PHASE3
Status: Active Not Recruiting → Completed
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Jul 2020 — Sep 2020 [monthly]
Active Not Recruiting PHASE3
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Jun 2020 — Jul 2020 [monthly]
Active Not Recruiting PHASE3
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May 2020 — Jun 2020 [monthly]
Active Not Recruiting PHASE3
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Apr 2020 — May 2020 [monthly]
Active Not Recruiting PHASE3
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Mar 2020 — Apr 2020 [monthly]
Active Not Recruiting PHASE3
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Feb 2020 — Mar 2020 [monthly]
Active Not Recruiting PHASE3
Status: Recruiting → Active Not Recruiting
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Jan 2020 — Feb 2020 [monthly]
Recruiting PHASE3
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Dec 2019 — Jan 2020 [monthly]
Recruiting PHASE3
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Nov 2019 — Dec 2019 [monthly]
Recruiting PHASE3
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Oct 2019 — Nov 2019 [monthly]
Recruiting PHASE3
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Sep 2019 — Oct 2019 [monthly]
Recruiting PHASE3
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Aug 2019 — Sep 2019 [monthly]
Recruiting PHASE3
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Jul 2019 — Aug 2019 [monthly]
Recruiting PHASE3
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Jun 2019 — Jul 2019 [monthly]
Recruiting PHASE3
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May 2019 — Jun 2019 [monthly]
Recruiting PHASE3
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Apr 2019 — May 2019 [monthly]
Recruiting PHASE3
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Mar 2019 — Apr 2019 [monthly]
Recruiting PHASE3
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Feb 2019 — Mar 2019 [monthly]
Recruiting PHASE3
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Jan 2019 — Feb 2019 [monthly]
Recruiting PHASE3
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Dec 2018 — Jan 2019 [monthly]
Recruiting PHASE3
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Nov 2018 — Dec 2018 [monthly]
Recruiting PHASE3
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Oct 2018 — Nov 2018 [monthly]
Recruiting PHASE3
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Sep 2018 — Oct 2018 [monthly]
Recruiting PHASE3
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Aug 2018 — Sep 2018 [monthly]
Recruiting PHASE3
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Jul 2018 — Aug 2018 [monthly]
Recruiting PHASE3
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Jun 2018 — Jul 2018 [monthly]
Recruiting PHASE3
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May 2018 — Jun 2018 [monthly]
Recruiting PHASE3
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Apr 2018 — May 2018 [monthly]
Recruiting PHASE3
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Mar 2018 — Apr 2018 [monthly]
Recruiting PHASE3
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Feb 2018 — Mar 2018 [monthly]
Recruiting PHASE3
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Jan 2018 — Feb 2018 [monthly]
Recruiting PHASE3
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Dec 2017 — Jan 2018 [monthly]
Recruiting PHASE3
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Nov 2017 — Dec 2017 [monthly]
Recruiting PHASE3
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Oct 2017 — Nov 2017 [monthly]
Recruiting PHASE3
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Aug 2017 — Oct 2017 [monthly]
Recruiting PHASE3
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Jul 2017 — Aug 2017 [monthly]
Recruiting PHASE3
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Jun 2017 — Jul 2017 [monthly]
Recruiting PHASE3
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May 2017 — Jun 2017 [monthly]
Recruiting PHASE3
Status: Not Yet Recruiting → Recruiting
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Mar 2017 — May 2017 [monthly]
Not Yet Recruiting PHASE3
First recorded
Eligibility Summary
No eligibility information available.
Contact Information
- Boehringer Ingelheim
- Eli Lilly and Company
For direct contact, visit the study record on ClinicalTrials.gov .