A Study of Pembrolizumab (MK-3475) in Combination With Etoposide/Platinum (Cisplatin or Carboplatin) for Participants With Extensive Stage Small Cell Lung Cancer (MK-3475-604/KEYNOTE-604)
A Phase 3 Randomized, Double-Blind, Placebo-controlled Trial of Pembrolizumab (MK-3475/SCH900475) in Combination With Etoposide/Platinum (Cisplatin or Carboplatin) for the First-line Treatment of Subjects With Extensive Stage Small Cell Lung Cancer (KEYNOTE-604)
Sponsor: Merck Sharp & Dohme LLC
A PHASE3 clinical study on Small Cell Lung Cancer (SCLC), this trial is completed. The trial is conducted by Merck Sharp & Dohme LLC and has accumulated 30 data snapshots since 2017. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.
Status Flow
Change History
30 versions recorded-
Dec 2025 — Present [monthly]
Completed PHASE3
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Sep 2025 — Dec 2025 [monthly]
Completed PHASE3
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Sep 2024 — Sep 2025 [monthly]
Completed PHASE3
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Jul 2024 — Sep 2024 [monthly]
Completed PHASE3
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Nov 2022 — Jul 2024 [monthly]
Completed PHASE3
▶ Show 25 earlier versions
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Jun 2022 — Nov 2022 [monthly]
Completed PHASE3
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Nov 2021 — Jun 2022 [monthly]
Completed PHASE3
Status: Active Not Recruiting → Completed
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Sep 2021 — Nov 2021 [monthly]
Active Not Recruiting PHASE3
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Apr 2021 — Sep 2021 [monthly]
Active Not Recruiting PHASE3
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Feb 2021 — Apr 2021 [monthly]
Active Not Recruiting PHASE3
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Jan 2021 — Feb 2021 [monthly]
Active Not Recruiting PHASE3
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Dec 2020 — Jan 2021 [monthly]
Active Not Recruiting PHASE3
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Feb 2020 — Dec 2020 [monthly]
Active Not Recruiting PHASE3
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Mar 2019 — Feb 2020 [monthly]
Active Not Recruiting PHASE3
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Jan 2019 — Mar 2019 [monthly]
Active Not Recruiting PHASE3
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Nov 2018 — Jan 2019 [monthly]
Active Not Recruiting PHASE3
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Aug 2018 — Nov 2018 [monthly]
Active Not Recruiting PHASE3
Status: Recruiting → Active Not Recruiting
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Jul 2018 — Aug 2018 [monthly]
Recruiting PHASE3
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Jun 2018 — Jul 2018 [monthly]
Recruiting PHASE3
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Mar 2018 — Jun 2018 [monthly]
Recruiting PHASE3
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Feb 2018 — Mar 2018 [monthly]
Recruiting PHASE3
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Jan 2018 — Feb 2018 [monthly]
Recruiting PHASE3
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Dec 2017 — Jan 2018 [monthly]
Recruiting PHASE3
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Nov 2017 — Dec 2017 [monthly]
Recruiting PHASE3
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Oct 2017 — Nov 2017 [monthly]
Recruiting PHASE3
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Sep 2017 — Oct 2017 [monthly]
Recruiting PHASE3
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Aug 2017 — Sep 2017 [monthly]
Recruiting PHASE3
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Jul 2017 — Aug 2017 [monthly]
Recruiting PHASE3
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Jun 2017 — Jul 2017 [monthly]
Recruiting PHASE3
Status: Not Yet Recruiting → Recruiting
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Mar 2017 — Jun 2017 [monthly]
Not Yet Recruiting PHASE3
First recorded
Eligibility Summary
No eligibility information available.
Contact Information
- Merck Sharp & Dohme LLC
For direct contact, visit the study record on ClinicalTrials.gov .