deltatrials
Completed PHASE1 INTERVENTIONAL 2-arm NCT03074006

Dose Escalation and Proof-of-Concept Studies of Vactosertib (TEW-7197) Monotherapy in Patients With MDS

Phase 1/2 Study of Vactosertib (TEW-7197) Monotherapy in Patients With Low or Intermediate Myelodysplastic Syndromes

Sponsor: MedPacto, Inc.

Conditions Myelodysplastic Syndromes
Interventions TEW-7197
Updated 15 times since 2017 Last updated: Sep 22, 2021 Started: Jan 4, 2018 Primary completion: Dec 31, 2019 Completion: Dec 31, 2019
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT03074006, this PHASE1 trial focuses on Myelodysplastic Syndromes and remains completed. Sponsored by MedPacto, Inc., it has been updated 15 times since 2018, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~May 2017 – ~Sep 2017 · 4 months · monthly snapshot~Sep 2017 – ~Dec 2017 · 3 months · monthly snapshot~Dec 2017 – ~Feb 2018 · 2 months · monthly snapshot~Feb 2018 – ~Jun 2018 · 4 months · monthly snapshot~Jun 2018 – ~Apr 2019 · 10 months · monthly snapshot~Apr 2019 – ~Jun 2019 · 2 months · monthly snapshot~Jun 2019 – ~Apr 2020 · 10 months · monthly snapshot~Apr 2020 – ~Jan 2021 · 9 months · monthly snapshot~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~May 2021 · 2 months · monthly snapshot~May 2021 – ~Oct 2021 · 5 months · monthly snapshot~Oct 2021 – ~Jul 2024 · 33 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 11 months · monthly snapshot

Change History

15 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed PHASE1

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  4. Oct 2021 — Jul 2024 [monthly]

    Completed PHASE1

    Status: Active Not Recruiting → Completed · Phase: PHASE1_PHASE2 → PHASE1

  5. May 2021 — Oct 2021 [monthly]

    Active Not Recruiting PHASE1_PHASE2

▶ Show 10 earlier versions

  1. Mar 2021 — May 2021 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  2. Jan 2021 — Mar 2021 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  3. Apr 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE1_PHASE2

    Status: Recruiting → Active Not Recruiting

  4. Jun 2019 — Apr 2020 [monthly]

    Recruiting PHASE1_PHASE2

  5. Apr 2019 — Jun 2019 [monthly]

    Recruiting PHASE1_PHASE2

  6. Jun 2018 — Apr 2019 [monthly]

    Recruiting PHASE1_PHASE2

  7. Feb 2018 — Jun 2018 [monthly]

    Recruiting PHASE1_PHASE2

    Status: Not Yet Recruiting → Recruiting

  8. Dec 2017 — Feb 2018 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

  9. Sep 2017 — Dec 2017 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

  10. May 2017 — Sep 2017 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • MedPacto, Inc.
Data source: MedPacto, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations