deltatrials
Recruiting PHASE1/PHASE2 INTERVENTIONAL 1-arm NCT05588648

Study to Assess Safety and Efficacy of Vactosertib in Adolescents and Adults With Recurrent, Refractory or Progressive Osteosarcoma

A Phase I/II, Open-label, Multicenter Study to Assess the Safety, Tolerability, Pharmacokinetics, and Antitumor Activity of Vactosertib as a Single Agent in Adolescents and Adults With Recurrent, Refractory or Progressive Osteosarcoma

Sponsor: MedPacto, Inc.

Conditions Osteosarcoma
Interventions Vactosertib
Updated 10 times since 2022 Last updated: Apr 8, 2025 Started: May 1, 2023 Primary completion: Sep 30, 2025 Completion: Dec 31, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT05588648, this PHASE1/PHASE2 trial focuses on Osteosarcoma and remains actively recruiting participants. Sponsored by MedPacto, Inc., it has been updated 10 times since 2023, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Nov 2022 – ~Mar 2023 · 4 months · monthly snapshotNot Yet Recruiting~Mar 2023 – ~May 2023 · 2 months · monthly snapshotNot Yet Recruiting~May 2023 – ~Feb 2024 · 9 months · monthly snapshotNot Yet Recruiting~Feb 2024 – ~Jun 2024 · 4 months · monthly snapshotRecruiting~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotRecruiting~Sep 2024 – ~Apr 2025 · 7 months · monthly snapshotRecruiting~Apr 2025 – ~May 2025 · 30 days · monthly snapshotRecruiting~May 2025 – ~Sep 2025 · 4 months · monthly snapshotRecruiting~Sep 2025 – present · 10 months · monthly snapshotRecruiting

Change History

10 versions recorded
  1. Sep 2025 — Present [monthly]

    Recruiting PHASE1/PHASE2

  2. May 2025 — Sep 2025 [monthly]

    Recruiting PHASE1/PHASE2

  3. Apr 2025 — May 2025 [monthly]

    Recruiting PHASE1/PHASE2

  4. Sep 2024 — Apr 2025 [monthly]

    Recruiting PHASE1/PHASE2

  5. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE1/PHASE2

    Phase: PHASE1_PHASE2PHASE1/PHASE2

Show 5 earlier versions
  1. Jun 2024 — Jul 2024 [monthly]

    Recruiting PHASE1_PHASE2

  2. Feb 2024 — Jun 2024 [monthly]

    Recruiting PHASE1_PHASE2

    Status: Not Yet RecruitingRecruiting

  3. May 2023 — Feb 2024 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

  4. Mar 2023 — May 2023 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

  5. Nov 2022 — Mar 2023 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • MedPacto, Inc.
Data source: MedPacto, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .