deltatrials
Completed OBSERVATIONAL NCT03078036

International Breast Cancer Biomarker,Standard of Care and Real World Outcomes Study (BREAKOUT)

BREAKOUT -International Breast Cancer Biomarker, Standard of Care and Real World Outcomes Study

Sponsor: AstraZeneca

Conditions Breast Cancer
Interventions Follow-up FoundationOne Dx Genomic Profile (archival Tumour Specimen) Germline BRCA Test (blood)
Updated 22 times since 2017 Last updated: May 19, 2020 Started: Mar 13, 2017 Primary completion: May 20, 2019 Completion: May 20, 2019
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This observational or N/A phase trial investigates Breast Cancer and is currently completed. AstraZeneca leads this study, which shows 22 recorded versions since 2017 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~May 2017 – ~Jul 2017 · 2 months · monthly snapshot~Jul 2017 – ~Aug 2017 · 31 days · monthly snapshot~Aug 2017 – ~Sep 2017 · 31 days · monthly snapshot~Sep 2017 – ~Oct 2017 · 30 days · monthly snapshot~Oct 2017 – ~Nov 2017 · 31 days · monthly snapshot~Nov 2017 – ~Dec 2017 · 30 days · monthly snapshot~Dec 2017 – ~Mar 2018 · 3 months · monthly snapshot~Mar 2018 – ~Apr 2018 · 31 days · monthly snapshot~Apr 2018 – ~May 2018 · 30 days · monthly snapshot~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Jul 2019 · 12 months · monthly snapshot~Jul 2019 – ~Sep 2019 · 2 months · monthly snapshot~Sep 2019 – ~Jun 2020 · 9 months · monthly snapshot~Jun 2020 – ~Nov 2020 · 5 months · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Dec 2021 · 11 months · monthly snapshot~Dec 2021 – ~Jul 2024 · 31 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – ~Dec 2025 · 3 months · monthly snapshot~Dec 2025 – present · 7 months · monthly snapshot

Change History

22 versions recorded

  1. Dec 2025 — Present [monthly]

    Completed

  2. Sep 2025 — Dec 2025 [monthly]

    Completed

  3. Sep 2024 — Sep 2025 [monthly]

    Completed

  4. Jul 2024 — Sep 2024 [monthly]

    Completed

  5. Dec 2021 — Jul 2024 [monthly]

    Completed

▶ Show 17 earlier versions

  1. Jan 2021 — Dec 2021 [monthly]

    Completed

  2. Nov 2020 — Jan 2021 [monthly]

    Completed

  3. Jun 2020 — Nov 2020 [monthly]

    Completed

  4. Sep 2019 — Jun 2020 [monthly]

    Completed

    Status: Active Not Recruiting → Completed

  5. Jul 2019 — Sep 2019 [monthly]

    Active Not Recruiting

  6. Jul 2018 — Jul 2019 [monthly]

    Active Not Recruiting

    Status: Recruiting → Active Not Recruiting

  7. Jun 2018 — Jul 2018 [monthly]

    Recruiting

  8. May 2018 — Jun 2018 [monthly]

    Recruiting

  9. Apr 2018 — May 2018 [monthly]

    Recruiting

    Phase: NA → None

  10. Mar 2018 — Apr 2018 [monthly]

    Recruiting NA

  11. Dec 2017 — Mar 2018 [monthly]

    Recruiting NA

  12. Nov 2017 — Dec 2017 [monthly]

    Recruiting NA

  13. Oct 2017 — Nov 2017 [monthly]

    Recruiting NA

  14. Sep 2017 — Oct 2017 [monthly]

    Recruiting NA

  15. Aug 2017 — Sep 2017 [monthly]

    Recruiting NA

  16. Jul 2017 — Aug 2017 [monthly]

    Recruiting NA

  17. May 2017 — Jul 2017 [monthly]

    Recruiting NA

    First recorded

Mar 2017

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • AstraZeneca
  • Quintiles; University of Tubingen - Germany
Data source: AstraZeneca

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

A Coruña, Spain , Adana, Turkey (Türkiye) , Alcorcón, Spain , Ankara, Turkey (Türkiye) , Antalya, Turkey (Türkiye) , Ballarat, Australia , Barcelona, Spain , Blackpool, United Kingdom , Brzozów, Poland , Budapest, Hungary and 87 more locations