deltatrials
Terminated PHASE2 INTERVENTIONAL 3-arm NCT03094195

Dose Response Study of EMA401 in Patients With Post-herpetic Neuralgia (PHN) (EMPHENE)

A Double-blind, Placebo-controlled, Randomized Dose Ranging Trial to Determine the Safety and Efficacy of Three Dose Levels of EMA401 in Reducing 24-hour Average Pain Intensity Score in Patients With Post-herpetic Neuralgia

Sponsor: Novartis Pharmaceuticals

Conditions Post-herpetic Neuralgia
Interventions EMA401 Placebo
Updated 27 times since 2017 Last updated: Oct 7, 2021 Started: Jun 27, 2017 Primary completion: Mar 7, 2019 Completion: Mar 7, 2019
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

The study was terminated early due to pre-clinical toxicity data that became available after start of trial

Other terminated trials from Novartis Pharmaceuticals

See all terminations from Novartis Pharmaceuticals

A PHASE2 clinical study on Post-herpetic Neuralgia, this trial is terminated or withdrawn. The trial is conducted by Novartis Pharmaceuticals and has accumulated 27 data snapshots since 2017. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~May 2017 – ~Aug 2017 · 3 months · monthly snapshot~Aug 2017 – ~Oct 2017 · 2 months · monthly snapshot~Oct 2017 – ~Nov 2017 · 31 days · monthly snapshot~Nov 2017 – ~Dec 2017 · 30 days · monthly snapshot~Dec 2017 – ~Jun 2018 · 6 months · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Aug 2018 · 31 days · monthly snapshot~Aug 2018 – ~Nov 2018 · 3 months · monthly snapshot~Nov 2018 – ~Dec 2018 · 30 days · monthly snapshot~Dec 2018 – ~Jan 2019 · 31 days · monthly snapshot~Jan 2019 – ~Feb 2019 · 31 days · monthly snapshot~Feb 2019 – ~Mar 2019 · 28 days · monthly snapshot~Mar 2019 – ~Apr 2019 · 31 days · monthly snapshot~Apr 2019 – ~May 2019 · 30 days · monthly snapshot~May 2019 – ~Jun 2019 · 31 days · monthly snapshot~Jun 2019 – ~Nov 2019 · 5 months · monthly snapshot~Nov 2019 – ~Jan 2020 · 2 months · monthly snapshot~Jan 2020 – ~Jun 2020 · 5 months · monthly snapshot~Jun 2020 – ~Nov 2020 · 5 months · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Nov 2021 · 10 months · monthly snapshot~Nov 2021 – ~Dec 2021 · 30 days · monthly snapshot~Dec 2021 – ~Jul 2024 · 31 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – ~Dec 2025 · 3 months · monthly snapshot~Dec 2025 – present · 7 months · monthly snapshot

Change History

27 versions recorded

  1. Dec 2025 — Present [monthly]

    Terminated PHASE2

  2. Sep 2025 — Dec 2025 [monthly]

    Terminated PHASE2

  3. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE2

  4. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE2

  5. Dec 2021 — Jul 2024 [monthly]

    Terminated PHASE2

▶ Show 22 earlier versions

  1. Nov 2021 — Dec 2021 [monthly]

    Terminated PHASE2

  2. Jan 2021 — Nov 2021 [monthly]

    Terminated PHASE2

  3. Nov 2020 — Jan 2021 [monthly]

    Terminated PHASE2

  4. Jun 2020 — Nov 2020 [monthly]

    Terminated PHASE2

    Status: Completed → Terminated

  5. Jan 2020 — Jun 2020 [monthly]

    Completed PHASE2

    Status: Terminated → Completed

  6. Nov 2019 — Jan 2020 [monthly]

    Terminated PHASE2

  7. Jun 2019 — Nov 2019 [monthly]

    Terminated PHASE2

  8. May 2019 — Jun 2019 [monthly]

    Terminated PHASE2

    Status: Recruiting → Terminated

  9. Apr 2019 — May 2019 [monthly]

    Recruiting PHASE2

  10. Mar 2019 — Apr 2019 [monthly]

    Recruiting PHASE2

  11. Feb 2019 — Mar 2019 [monthly]

    Recruiting PHASE2

  12. Jan 2019 — Feb 2019 [monthly]

    Recruiting PHASE2

  13. Dec 2018 — Jan 2019 [monthly]

    Recruiting PHASE2

  14. Nov 2018 — Dec 2018 [monthly]

    Recruiting PHASE2

  15. Aug 2018 — Nov 2018 [monthly]

    Recruiting PHASE2

  16. Jul 2018 — Aug 2018 [monthly]

    Recruiting PHASE2

  17. Jun 2018 — Jul 2018 [monthly]

    Recruiting PHASE2

  18. Dec 2017 — Jun 2018 [monthly]

    Recruiting PHASE2

  19. Nov 2017 — Dec 2017 [monthly]

    Recruiting PHASE2

  20. Oct 2017 — Nov 2017 [monthly]

    Recruiting PHASE2

  21. Aug 2017 — Oct 2017 [monthly]

    Recruiting PHASE2

    Status: Not Yet Recruiting → Recruiting

  22. May 2017 — Aug 2017 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Novartis Pharmaceuticals
Data source: Novartis

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Almada, Portugal , Aveiro, Portugal , Banská Bystrica, Slovakia , Barcelona, Spain , Berlin, Germany , Boulogne-Billancourt, France , Brno, Czechia , Choceň, Czechia , Clermont-Ferrand, France , Darlington, United Kingdom and 45 more locations