deltatrials
Completed NA INTERVENTIONAL 2-arm NCT03112200

Subchondroplasty® Knee RCT (PRESERVE Knee)

A Randomized Controlled Trial of the Subchondroplasty® Procedure With Arthroscopy Versus Arthroscopy Alone for Treatment of Bone Marrow Lesions in the Knee

Sponsor: MedNet Solutions

Conditions Bone Marrow Edema Knee Osteoarthritis Knee Pain Chronic Osteoarthritis Osteoarthritis, Knee
Interventions Arthroscopy Alone Subchondroplasty with Arthroscopy
Updated 26 times since 2017 Last updated: Sep 20, 2023 Started: Mar 29, 2017 Primary completion: Aug 23, 2023 Completion: Aug 23, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This NA trial investigates Bone Marrow Edema and Knee Osteoarthritis and is currently completed. MedNet Solutions leads this study, which shows 26 recorded versions since 2017 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~May 2017 – ~Aug 2017 · 3 months · monthly snapshot~Aug 2017 – ~Sep 2017 · 31 days · monthly snapshot~Sep 2017 – ~Nov 2017 · 2 months · monthly snapshot~Nov 2017 – ~Jan 2018 · 2 months · monthly snapshot~Jan 2018 – ~Mar 2018 · 59 days · monthly snapshot~Mar 2018 – ~Jun 2018 · 3 months · monthly snapshot~Jun 2018 – ~Sep 2018 · 3 months · monthly snapshot~Sep 2018 – ~Nov 2018 · 2 months · monthly snapshot~Nov 2018 – ~Dec 2018 · 30 days · monthly snapshot~Dec 2018 – ~Feb 2019 · 2 months · monthly snapshot~Feb 2019 – ~Mar 2019 · 28 days · monthly snapshot~Mar 2019 – ~Jul 2019 · 4 months · monthly snapshot~Jul 2019 – ~Nov 2019 · 4 months · monthly snapshot~Nov 2019 – ~Dec 2019 · 30 days · monthly snapshot~Dec 2019 – ~Feb 2020 · 2 months · monthly snapshot~Feb 2020 – ~Apr 2020 · 2 months · monthly snapshot~Apr 2020 – ~Nov 2020 · 7 months · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshot~Sep 2021 – ~Nov 2021 · 2 months · monthly snapshot~Nov 2021 – ~Nov 2022 · 12 months · monthly snapshot~Nov 2022 – ~Sep 2023 · 10 months · monthly snapshot~Sep 2023 – ~Oct 2023 · 30 days · monthly snapshot~Oct 2023 – ~Jul 2024 · 9 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 22 months · monthly snapshot

Change History

26 versions recorded

  1. Sep 2024 — Present [monthly]

    Completed NA

  2. Jul 2024 — Sep 2024 [monthly]

    Completed NA

  3. Oct 2023 — Jul 2024 [monthly]

    Completed NA

    Status: Active Not Recruiting → Completed

  4. Sep 2023 — Oct 2023 [monthly]

    Active Not Recruiting NA

  5. Nov 2022 — Sep 2023 [monthly]

    Active Not Recruiting NA

▶ Show 21 earlier versions

  1. Nov 2021 — Nov 2022 [monthly]

    Active Not Recruiting NA

  2. Sep 2021 — Nov 2021 [monthly]

    Active Not Recruiting NA

  3. Jan 2021 — Sep 2021 [monthly]

    Active Not Recruiting NA

  4. Nov 2020 — Jan 2021 [monthly]

    Active Not Recruiting NA

    Status: Recruiting → Active Not Recruiting

  5. Apr 2020 — Nov 2020 [monthly]

    Recruiting NA

  6. Feb 2020 — Apr 2020 [monthly]

    Recruiting NA

  7. Dec 2019 — Feb 2020 [monthly]

    Recruiting NA

  8. Nov 2019 — Dec 2019 [monthly]

    Recruiting NA

  9. Jul 2019 — Nov 2019 [monthly]

    Recruiting NA

  10. Mar 2019 — Jul 2019 [monthly]

    Recruiting NA

  11. Feb 2019 — Mar 2019 [monthly]

    Recruiting NA

  12. Dec 2018 — Feb 2019 [monthly]

    Recruiting NA

  13. Nov 2018 — Dec 2018 [monthly]

    Recruiting NA

  14. Sep 2018 — Nov 2018 [monthly]

    Recruiting NA

  15. Jun 2018 — Sep 2018 [monthly]

    Recruiting NA

  16. Mar 2018 — Jun 2018 [monthly]

    Recruiting NA

  17. Jan 2018 — Mar 2018 [monthly]

    Recruiting NA

  18. Nov 2017 — Jan 2018 [monthly]

    Recruiting NA

  19. Sep 2017 — Nov 2017 [monthly]

    Recruiting NA

  20. Aug 2017 — Sep 2017 [monthly]

    Recruiting NA

  21. May 2017 — Aug 2017 [monthly]

    Recruiting NA

    First recorded

Mar 2017

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • MedNet Solutions
  • Medical Metrics Diagnostics, Inc
  • Zimmer Biomet
Data source: Zimmer Biomet

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Albuquerque, United States , Atlanta, United States , Austin, United States , Charlottesville, United States , Chicago, United States , Columbus, United States , Encinitas, United States , Greenville, United States , Hamilton, Canada , Loma Linda, United States and 3 more locations