deltatrials
Terminated PHASE3 INTERVENTIONAL 2-arm NCT04140695

Evaluating the Effects of Tradipitant vs. Placebo in Atopic Dermatitis (EPIONE2)

A Randomized, Double-blind, Placebo-controlled, Efficacy Study of the Neurokinin-1 Receptor Antagonist VLY-686 in Patients With Atopic Dermatitis

Sponsor: Vanda Pharmaceuticals

Updated 10 times since 2019 Last updated: Apr 23, 2024 Started: Oct 21, 2019 Primary completion: Oct 14, 2020 Completion: Oct 14, 2020
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Business Decision

Listed as NCT04140695, this PHASE3 trial focuses on Atopic Dermatitis and remains terminated or withdrawn. Sponsored by Vanda Pharmaceuticals, it has been updated 10 times since 2019, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Nov 2019 – ~Dec 2019 · 30 days · monthly snapshotRecruiting~Dec 2019 – ~May 2020 · 5 months · monthly snapshotRecruiting~May 2020 – ~Jun 2020 · 31 days · monthly snapshotRecruiting~Jun 2020 – ~Jan 2021 · 7 months · monthly snapshotRecruiting~Jan 2021 – ~Jun 2022 · 17 months · monthly snapshotRecruiting~Jun 2022 – ~Jun 2024 · 24 months · monthly snapshotCompleted~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotTerminated~Sep 2025 – present · 10 months · monthly snapshotTerminated

Change History

10 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE3

  4. Jun 2024 — Jul 2024 [monthly]

    Terminated PHASE3

    Status: CompletedTerminated

  5. Jun 2022 — Jun 2024 [monthly]

    Completed PHASE3

    Status: RecruitingCompleted

Show 5 earlier versions
  1. Jan 2021 — Jun 2022 [monthly]

    Recruiting PHASE3

  2. Jun 2020 — Jan 2021 [monthly]

    Recruiting PHASE3

  3. May 2020 — Jun 2020 [monthly]

    Recruiting PHASE3

  4. Dec 2019 — May 2020 [monthly]

    Recruiting PHASE3

  5. Nov 2019 — Dec 2019 [monthly]

    Recruiting PHASE3

    First recorded

Oct 2019

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Vanda Pharmaceuticals
Data source: Vanda Pharmaceuticals

For direct contact, visit the study record on ClinicalTrials.gov .