Active Not Recruiting NA INTERVENTIONAL 1-arm NCT03115333

DSC-MRI in Measuring rCBV for Early Response to Bevacizumab in Patients With Recurrent Glioblastoma

Change in Relative Cerebral Blood Volume as a Biomarker for Early Response to Bevacizumab in Patients With Recurrent Glioblastoma

Sponsor: ECOG-ACRIN Cancer Research Group

Conditions Gliosarcoma Recurrent Glioblastoma

Interventions Dynamic Susceptibility Contrast-Enhanced Magnetic Resonance Imaging

Updated 24 times since 2017 Last updated: Feb 27, 2026 Started: Jul 25, 2017 Primary completion: Dec 31, 2025 Completion: May 7, 2027

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A NA clinical study on Gliosarcoma and Recurrent Glioblastoma, this trial is ongoing. The trial is conducted by ECOG-ACRIN Cancer Research Group and has accumulated 24 data snapshots since 2017. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

Change History

24 versions recorded

Mar 2026 — Present [monthly]

Active Not Recruiting NA
Feb 2026 — Mar 2026 [monthly]

Active Not Recruiting NA
Jan 2026 — Feb 2026 [monthly]

Active Not Recruiting NA
Dec 2025 — Jan 2026 [monthly]

Active Not Recruiting NA
Nov 2025 — Dec 2025 [monthly]

Active Not Recruiting NA

▶ Show 19 earlier versions

Oct 2025 — Nov 2025 [monthly]

Active Not Recruiting NA

Status: Recruiting → Active Not Recruiting
Sep 2025 — Oct 2025 [monthly]

Recruiting NA
Apr 2025 — Sep 2025 [monthly]

Recruiting NA
Sep 2024 — Apr 2025 [monthly]

Recruiting NA
Aug 2024 — Sep 2024 [monthly]

Recruiting NA
Jul 2024 — Aug 2024 [monthly]

Recruiting NA
Jul 2023 — Jul 2024 [monthly]

Recruiting NA
Jul 2022 — Jul 2023 [monthly]

Recruiting NA
Jan 2022 — Jul 2022 [monthly]

Recruiting NA
Nov 2021 — Jan 2022 [monthly]

Recruiting NA

Phase: PHASE2 → NA
Jan 2021 — Nov 2021 [monthly]

Recruiting PHASE2
Jun 2020 — Jan 2021 [monthly]

Recruiting PHASE2
Mar 2020 — Jun 2020 [monthly]

Recruiting PHASE2
Feb 2020 — Mar 2020 [monthly]

Recruiting PHASE2
Nov 2019 — Feb 2020 [monthly]

Recruiting PHASE2
Feb 2019 — Nov 2019 [monthly]

Recruiting PHASE2
Jun 2018 — Feb 2019 [monthly]

Recruiting PHASE2
Dec 2017 — Jun 2018 [monthly]

Recruiting PHASE2

Phase: NA → PHASE2
May 2017 — Dec 2017 [monthly]

Recruiting NA

First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Data source: Eastern Cooperative Oncology Group

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Albuquerque, United States , Atlanta, United States , Baltimore, United States , Boca Raton, United States , Castro Valley, United States , Chapel Hill, United States , Charlotte, United States , Cincinnati, United States , City of Saint Peters, United States , Columbia, United States and 36 more locations