deltatrials
Completed PHASE2 INTERVENTIONAL 2-arm NCT03122509

A Clinical Trial of Durvalumab and Tremelimumab, Administered With Radiation Therapy or Ablation in Patients With Colorectal Cancer

Phase II Study to Assess the Efficacy of Durvalumab (MEDI4736) and Tremelimumab Plus Radiotherapy or Ablation in Patients With Metastatic Colorectal Cancer

Sponsor: AstraZeneca

Updated 14 times since 2017 Last updated: Jun 15, 2022 Started: Apr 24, 2017 Primary completion: Apr 28, 2021 Completion: Apr 28, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Metastatic Colorectal Cancer, this trial is completed. The trial is conducted by AstraZeneca and has accumulated 14 data snapshots since 2017. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~May 2017 – ~Jun 2017 · 31 days · monthly snapshot~Jun 2017 – ~Jun 2018 · 12 months · monthly snapshot~Jun 2018 – ~Nov 2018 · 5 months · monthly snapshot~Nov 2018 – ~Jun 2019 · 7 months · monthly snapshot~Jun 2019 – ~Mar 2020 · 9 months · monthly snapshot~Mar 2020 – ~Jan 2021 · 10 months · monthly snapshot~Jan 2021 – ~Apr 2021 · 3 months · monthly snapshot~Apr 2021 – ~May 2021 · 30 days · monthly snapshot~May 2021 – ~Sep 2022 · 16 months · monthly snapshot~Sep 2022 – ~Dec 2022 · 3 months · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Jul 2024 · 18 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 22 months · monthly snapshot

Change History

14 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  3. Jan 2023 — Jul 2024 [monthly]

    Completed PHASE2

  4. Dec 2022 — Jan 2023 [monthly]

    Completed PHASE2

  5. Sep 2022 — Dec 2022 [monthly]

    Completed PHASE2

Show 9 earlier versions
  1. May 2021 — Sep 2022 [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

  2. Apr 2021 — May 2021 [monthly]

    Active Not Recruiting PHASE2

  3. Jan 2021 — Apr 2021 [monthly]

    Active Not Recruiting PHASE2

  4. Mar 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  5. Jun 2019 — Mar 2020 [monthly]

    Recruiting PHASE2

  6. Nov 2018 — Jun 2019 [monthly]

    Recruiting PHASE2

  7. Jun 2018 — Nov 2018 [monthly]

    Recruiting PHASE2

  8. Jun 2017 — Jun 2018 [monthly]

    Recruiting PHASE2

  9. May 2017 — Jun 2017 [monthly]

    Recruiting PHASE2

    First recorded

Apr 2017

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • AstraZeneca
  • MedImmune LLC
  • Memorial Sloan Kettering Cancer Center
Data source: Memorial Sloan Kettering Cancer Center

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations