deltatrials
Terminated PHASE2 INTERVENTIONAL 2-arm NCT03152786

Propranolol Hydrochloride in Treating Patients With Prostate Cancer Undergoing Surgery

Evaluating the Effect of ADRB2 Blockers on PKA/BAD/CREB Signaling in Patients Undergoing Prostatectomy

Sponsor: National Cancer Institute (NCI)

Conditions Prostate Carcinoma
Interventions Laboratory Biomarker Analysis Propranolol Hydrochloride Questionnaire Administration Survey Administration
Updated 22 times since 2017 Last updated: Jan 29, 2025 Started: Jan 15, 2019 Primary completion: Jun 15, 2021 Completion: Feb 28, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

PIs not interested in continuing with the trial.

Other terminated trials from National Cancer Institute (NCI)

See all terminations from National Cancer Institute (NCI)

Other Prostate Carcinoma trials with similar outcome

Browse all Prostate Carcinoma trials

Listed as NCT03152786, this PHASE2 trial focuses on Prostate Carcinoma and remains terminated or withdrawn. Sponsored by National Cancer Institute (NCI), it has been updated 22 times since 2019, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jul 2017 – ~Mar 2018 · 8 months · monthly snapshot~Mar 2018 – ~Jun 2018 · 3 months · monthly snapshot~Jun 2018 – ~Aug 2018 · 2 months · monthly snapshot~Aug 2018 – ~Apr 2019 · 8 months · monthly snapshot~Apr 2019 – ~Sep 2019 · 5 months · monthly snapshot~Sep 2019 – ~Dec 2019 · 3 months · monthly snapshot~Dec 2019 – ~Mar 2020 · 3 months · monthly snapshot~Mar 2020 – ~Apr 2020 · 31 days · monthly snapshot~Apr 2020 – ~Jul 2020 · 3 months · monthly snapshot~Jul 2020 – ~Jan 2021 · 6 months · monthly snapshot~Jan 2021 – ~May 2021 · 4 months · monthly snapshot~May 2021 – ~Sep 2021 · 4 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Feb 2022 · 4 months · monthly snapshot~Feb 2022 – ~Sep 2022 · 7 months · monthly snapshot~Sep 2022 – ~Jan 2023 · 4 months · monthly snapshot~Jan 2023 – ~Apr 2023 · 3 months · monthly snapshot~Apr 2023 – ~Aug 2023 · 4 months · monthly snapshot~Aug 2023 – ~Jul 2024 · 11 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Mar 2025 · 6 months · monthly snapshot~Mar 2025 – present · 18 months · monthly snapshot

Change History

22 versions recorded

  1. Mar 2025 — Present [monthly]

    Terminated PHASE2

  2. Sep 2024 — Mar 2025 [monthly]

    Terminated PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE2

  4. Aug 2023 — Jul 2024 [monthly]

    Terminated PHASE2

    Status: Active Not Recruiting → Terminated

  5. Apr 2023 — Aug 2023 [monthly]

    Active Not Recruiting PHASE2

    Status: Suspended → Active Not Recruiting

▶ Show 17 earlier versions

  1. Jan 2023 — Apr 2023 [monthly]

    Suspended PHASE2

  2. Sep 2022 — Jan 2023 [monthly]

    Suspended PHASE2

  3. Feb 2022 — Sep 2022 [monthly]

    Suspended PHASE2

  4. Oct 2021 — Feb 2022 [monthly]

    Suspended PHASE2

    Status: Recruiting → Suspended

  5. Sep 2021 — Oct 2021 [monthly]

    Recruiting PHASE2

  6. May 2021 — Sep 2021 [monthly]

    Recruiting PHASE2

  7. Jan 2021 — May 2021 [monthly]

    Recruiting PHASE2

  8. Jul 2020 — Jan 2021 [monthly]

    Recruiting PHASE2

    Status: Suspended → Recruiting

  9. Apr 2020 — Jul 2020 [monthly]

    Suspended PHASE2

    Status: Recruiting → Suspended

  10. Mar 2020 — Apr 2020 [monthly]

    Recruiting PHASE2

    Status: Suspended → Recruiting

  11. Dec 2019 — Mar 2020 [monthly]

    Suspended PHASE2

    Status: Recruiting → Suspended

  12. Sep 2019 — Dec 2019 [monthly]

    Recruiting PHASE2

  13. Apr 2019 — Sep 2019 [monthly]

    Recruiting PHASE2

  14. Aug 2018 — Apr 2019 [monthly]

    Recruiting PHASE2

  15. Jun 2018 — Aug 2018 [monthly]

    Recruiting PHASE2

  16. Mar 2018 — Jun 2018 [monthly]

    Recruiting PHASE2

    Status: Not Yet Recruiting → Recruiting

  17. Jul 2017 — Mar 2018 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • National Cancer Institute (NCI)
  • Wake Forest University Health Sciences
Data source: Wake Forest University Health Sciences

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations