deltatrials
Completed PHASE3 INTERVENTIONAL 2-arm NCT04467086

Propranolol as an Anxiolytic to Reduce the Use of Sedatives From Critically-ill Adults Receiving Mechanical Ventilation (PROACTIVE)

Propranolol as an Anxiolytic to Reduce the Use of Sedatives From Critically-ill Adults Receiving Mechanical Ventilation: An Open-label Randomized Controlled Trial (PROACTIVE)

Sponsor: Hamilton Health Sciences Corporation

Updated 8 times since 2020 Last updated: Dec 1, 2022 Started: Jan 8, 2021 Primary completion: Nov 30, 2022 Completion: Nov 30, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT04467086, this PHASE3 trial focuses on COVID and Critical Illness and remains completed. Sponsored by Hamilton Health Sciences Corporation, it has been updated 8 times since 2021, reflecting limited change activity. This study is part of the global effort to build evidence for infectious disease interventions.

Status Flow

~Aug 2020 – ~Sep 2020 · 31 days · monthly snapshotNot Yet Recruiting~Sep 2020 – ~Dec 2020 · 3 months · monthly snapshotNot Yet Recruiting~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshotNot Yet Recruiting~Jan 2021 – ~Jun 2021 · 5 months · monthly snapshotRecruiting~Jun 2021 – ~Jan 2023 · 19 months · monthly snapshotRecruiting~Jan 2023 – ~Jul 2024 · 18 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 23 months · monthly snapshotCompleted

Change History

8 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE3

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  3. Jan 2023 — Jul 2024 [monthly]

    Completed PHASE3

    Status: RecruitingCompleted

  4. Jun 2021 — Jan 2023 [monthly]

    Recruiting PHASE3

  5. Jan 2021 — Jun 2021 [monthly]

    Recruiting PHASE3

    Status: Not Yet RecruitingRecruiting

Show 3 earlier versions
  1. Dec 2020 — Jan 2021 [monthly]

    Not Yet Recruiting PHASE3

  2. Sep 2020 — Dec 2020 [monthly]

    Not Yet Recruiting PHASE3

  3. Aug 2020 — Sep 2020 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Hamilton Health Sciences Corporation
  • McMaster University
  • Ottawa Hospital Research Institute
  • Sinai Health System
  • The Ottawa Hospital
Data source: Ottawa Hospital Research Institute

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations