Completed PHASE3 INTERVENTIONAL 2-arm NCT03153150

Start or STop Anticoagulants Randomised Trial (SoSTART) (SoSTART)

Start or STop Anticoagulants Randomised Trial (SoSTART) After Spontaneous Intracranial Haemorrhage

Sponsor: NHS Lothian

Conditions Atrial Fibrillation Atrial Flutter Intracranial Hemorrhage, Hypertensive Intracranial Hemorrhages Intraventricular Hemorrhage Microhaemorrhage Small Vessel Cerebrovascular Disease Subarachnoid Hemorrhage Subdural Hematoma

Interventions Acenocoumarol Apixaban Dabigatran Edoxaban Phenindione Rivaroxaban Warfarin

Updated 11 times since 2017 Last updated: Mar 31, 2022 Started: Mar 28, 2018 Primary completion: Mar 26, 2021 Completion: Mar 26, 2021

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Atrial Fibrillation and Atrial Flutter and is currently completed. NHS Lothian leads this study, which shows 11 recorded versions since 2018 — indicating substantial longitudinal coverage. Heart and vascular conditions benefit from the kind of long-term tracking this trial provides.

Status Flow

Change History

11 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE3
Sep 2024 — Sep 2025 [monthly]

Completed PHASE3
Jul 2024 — Sep 2024 [monthly]

Completed PHASE3
May 2022 — Jul 2024 [monthly]

Completed PHASE3
Jun 2021 — May 2022 [monthly]

Completed PHASE3

Status: Active Not Recruiting → Completed

▶ Show 6 earlier versions

Jan 2021 — Jun 2021 [monthly]

Active Not Recruiting PHASE3
Jul 2020 — Jan 2021 [monthly]

Active Not Recruiting PHASE3

Status: Recruiting → Active Not Recruiting
Dec 2019 — Jul 2020 [monthly]

Recruiting PHASE3
Jul 2018 — Dec 2019 [monthly]

Recruiting PHASE3
Jun 2018 — Jul 2018 [monthly]

Recruiting PHASE3

Status: Not Yet Recruiting → Recruiting
Jul 2017 — Jun 2018 [monthly]

Not Yet Recruiting PHASE3

First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

NHS Lothian
University of Edinburgh

Data source: University of Edinburgh

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Aberdeen, United Kingdom , Abergavenny, United Kingdom , Airdrie, United Kingdom , Barnet, United Kingdom , Bath, United Kingdom , Birmingham, United Kingdom , Bournemouth, United Kingdom , Bradford, United Kingdom , Bristol, United Kingdom , Cambridge, United Kingdom and 50 more locations