deltatrials
Completed NA INTERVENTIONAL 2-arm NCT03167580

REstricted Versus Liberal Positive End-Expiratory Pressure in Patients Without ARDS (RELAx)

REstricted Versus Liberal Positive End-Expiratory Pressure in Patients Without Acute Respiratory Distress Syndrome

Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Conditions Ventilator-free Days
Interventions liberal PEEP restricted PEEP
Updated 14 times since 2017 Last updated: Mar 30, 2020 Started: Oct 26, 2017 Primary completion: Jan 14, 2020 Completion: Mar 16, 2020
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This NA trial investigates Ventilator-free Days and is currently completed. Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) leads this study, which shows 14 recorded versions since 2017 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jul 2017 – ~Dec 2017 · 5 months · monthly snapshot~Dec 2017 – ~Jun 2018 · 6 months · monthly snapshot~Jun 2018 – ~Sep 2018 · 3 months · monthly snapshot~Sep 2018 – ~May 2019 · 8 months · monthly snapshot~May 2019 – ~Sep 2019 · 4 months · monthly snapshot~Sep 2019 – ~Oct 2019 · 30 days · monthly snapshot~Oct 2019 – ~Jan 2020 · 3 months · monthly snapshot~Jan 2020 – ~Apr 2020 · 3 months · monthly snapshot~Apr 2020 – ~Jan 2021 · 9 months · monthly snapshot~Jan 2021 – ~May 2022 · 16 months · monthly snapshot~May 2022 – ~Jul 2024 · 26 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

14 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed NA

  2. Sep 2024 — Sep 2025 [monthly]

    Completed NA

  3. Jul 2024 — Sep 2024 [monthly]

    Completed NA

  4. May 2022 — Jul 2024 [monthly]

    Completed NA

  5. Jan 2021 — May 2022 [monthly]

    Completed NA

▶ Show 9 earlier versions

  1. Apr 2020 — Jan 2021 [monthly]

    Completed NA

    Status: Recruiting → Completed

  2. Jan 2020 — Apr 2020 [monthly]

    Recruiting NA

  3. Oct 2019 — Jan 2020 [monthly]

    Recruiting NA

  4. Sep 2019 — Oct 2019 [monthly]

    Recruiting NA

  5. May 2019 — Sep 2019 [monthly]

    Recruiting NA

  6. Sep 2018 — May 2019 [monthly]

    Recruiting NA

  7. Jun 2018 — Sep 2018 [monthly]

    Recruiting NA

  8. Dec 2017 — Jun 2018 [monthly]

    Recruiting NA

    Status: Not Yet Recruiting → Recruiting

  9. Jul 2017 — Dec 2017 [monthly]

    Not Yet Recruiting NA

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
  • Amphia Hospital
  • Amsterdam UMC, location VUmc
  • Dijklander Ziekenhuis
  • Gelre Hospitals
  • HagaZiekenhuis
  • Isala
  • Maastricht University Medical Center
  • Medical Center Haaglanden
  • Onze Lieve Vrouwe Gasthuis
  • Rijnstate Hospital
  • Spaarne Gasthuis
  • St. Antonius Hospital
  • ZonMw: The Netherlands Organisation for Health Research and Development
Data source: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations