deltatrials
Unknown PHASE3 INTERVENTIONAL 2-arm NCT03181360

Tenecteplase in Wake-up Ischaemic Stroke Trial (TWIST)

Tenecteplase in Wake-up Ischaemic Stroke Trial (TWIST). A Randomised-controlled Trial of Thrombolytic Treatment With Tenecteplase for Acute Ischaemic Stroke Upon Awakening

Sponsor: Norwegian Health Association

Conditions Ischemic Stroke Stroke, Acute
Interventions Control Tenecteplase
Updated 14 times since 2017 Last updated: May 11, 2021 Started: Jun 12, 2017 Primary completion: Dec 31, 2021 Completion: Dec 31, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on Ischemic Stroke and Stroke, Acute, this trial is ongoing. The trial is conducted by Norwegian Health Association and has accumulated 14 data snapshots since 2017. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Jun 2017 – ~Aug 2017 · 2 months · monthly snapshot~Aug 2017 – ~Mar 2018 · 7 months · monthly snapshot~Mar 2018 – ~Jun 2018 · 3 months · monthly snapshot~Jun 2018 – ~May 2019 · 11 months · monthly snapshot~May 2019 – ~Apr 2020 · 11 months · monthly snapshot~Apr 2020 – ~Dec 2020 · 8 months · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Jun 2021 · 4 months · monthly snapshot~Jun 2021 – ~Jun 2023 · 24 months · monthly snapshot~Jun 2023 – ~Jul 2024 · 13 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

14 versions recorded

  1. Sep 2025 — Present [monthly]

    Unknown PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Unknown PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Unknown PHASE3

    Status: Unknown Status → Unknown

  4. Jun 2023 — Jul 2024 [monthly]

    Unknown Status PHASE3

    Status: Recruiting → Unknown Status

  5. Jun 2021 — Jun 2023 [monthly]

    Recruiting PHASE3

▶ Show 9 earlier versions

  1. Feb 2021 — Jun 2021 [monthly]

    Recruiting PHASE3

  2. Jan 2021 — Feb 2021 [monthly]

    Recruiting PHASE3

  3. Dec 2020 — Jan 2021 [monthly]

    Recruiting PHASE3

  4. Apr 2020 — Dec 2020 [monthly]

    Recruiting PHASE3

  5. May 2019 — Apr 2020 [monthly]

    Recruiting PHASE3

  6. Jun 2018 — May 2019 [monthly]

    Recruiting PHASE3

  7. Mar 2018 — Jun 2018 [monthly]

    Recruiting PHASE3

  8. Aug 2017 — Mar 2018 [monthly]

    Recruiting PHASE3

    Status: Not Yet Recruiting → Recruiting

  9. Jun 2017 — Aug 2017 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Norwegian Health Association
  • The Royal Norwegian Ministry of Health
  • UiT The Arctic University of Norway
  • University Hospital of North Norway
Data source: University Hospital of North Norway

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Aberdeen, United Kingdom , Alytus, Lithuania , Arendal, Norway , Basel, Switzerland , Birkenhead, United Kingdom , Birmingham, United Kingdom , Bournemouth, United Kingdom , Cambridge, United Kingdom , Chester, United Kingdom , Christchurch, New Zealand and 66 more locations