deltatrials
Recruiting PHASE3 INTERVENTIONAL 2-arm NCT03188796

The VITDALIZE Study: Effect of High-dose Vitamin D3 on 28-day Mortality in Adult Critically Ill Patients (VITDALIZE)

The VITDALIZE Study: Effect of High-dose Vitamin D3 on 28-day Mortality in Adult Critically Ill Patients With Severe Vitamin D Deficiency: a Multicenter, Placebo-controlled Double-blind Phase III Randomized Controlled Trial (RCT)

Sponsor: Barmherzige Brüder Vienna

Updated 29 times since 2017 Last updated: Nov 18, 2025 Started: Oct 10, 2017 Primary completion: Mar 31, 2027 Completion: Mar 31, 2027
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Covid19 and Critical Illness and is currently actively recruiting participants. Barmherzige Brüder Vienna leads this study, which shows 29 recorded versions since 2017 — indicating substantial longitudinal coverage. Longitudinal tracking of infectious disease trials helps identify durability of treatment effects.

Status Flow

~Jul 2017 – ~Nov 2017 · 4 months · monthly snapshot~Nov 2017 – ~Mar 2018 · 4 months · monthly snapshot~Mar 2018 – ~Jun 2018 · 3 months · monthly snapshot~Jun 2018 – ~Aug 2018 · 2 months · monthly snapshot~Aug 2018 – ~Feb 2019 · 6 months · monthly snapshot~Feb 2019 – ~Mar 2019 · 28 days · monthly snapshot~Mar 2019 – ~Aug 2019 · 5 months · monthly snapshot~Aug 2019 – ~Nov 2019 · 3 months · monthly snapshot~Nov 2019 – ~Jan 2020 · 2 months · monthly snapshot~Jan 2020 – ~Feb 2020 · 31 days · monthly snapshot~Feb 2020 – ~Jan 2021 · 11 months · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Jan 2022 · 11 months · monthly snapshot~Jan 2022 – ~Apr 2022 · 3 months · monthly snapshot~Apr 2022 – ~Jul 2022 · 3 months · monthly snapshot~Jul 2022 – ~Nov 2022 · 4 months · monthly snapshot~Nov 2022 – ~Jan 2023 · 2 months · monthly snapshot~Jan 2023 – ~Mar 2023 · 59 days · monthly snapshot~Mar 2023 – ~Jun 2023 · 3 months · monthly snapshot~Jun 2023 – ~Oct 2023 · 4 months · monthly snapshot~Oct 2023 – ~Feb 2024 · 4 months · monthly snapshot~Feb 2024 – ~Jun 2024 · 4 months · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Feb 2025 · 5 months · monthly snapshot~Feb 2025 – ~Mar 2025 · 28 days · monthly snapshot~Mar 2025 – ~Sep 2025 · 6 months · monthly snapshot~Sep 2025 – ~Dec 2025 · 3 months · monthly snapshot~Dec 2025 – present · 7 months · monthly snapshot

Change History

29 versions recorded
  1. Dec 2025 — Present [monthly]

    Recruiting PHASE3

  2. Sep 2025 — Dec 2025 [monthly]

    Recruiting PHASE3

  3. Mar 2025 — Sep 2025 [monthly]

    Recruiting PHASE3

  4. Feb 2025 — Mar 2025 [monthly]

    Recruiting PHASE3

  5. Sep 2024 — Feb 2025 [monthly]

    Recruiting PHASE3

Show 24 earlier versions
  1. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE3

  2. Jun 2024 — Jul 2024 [monthly]

    Recruiting PHASE3

  3. Feb 2024 — Jun 2024 [monthly]

    Recruiting PHASE3

  4. Oct 2023 — Feb 2024 [monthly]

    Recruiting PHASE3

  5. Jun 2023 — Oct 2023 [monthly]

    Recruiting PHASE3

  6. Mar 2023 — Jun 2023 [monthly]

    Recruiting PHASE3

  7. Jan 2023 — Mar 2023 [monthly]

    Recruiting PHASE3

  8. Nov 2022 — Jan 2023 [monthly]

    Recruiting PHASE3

  9. Jul 2022 — Nov 2022 [monthly]

    Recruiting PHASE3

  10. Apr 2022 — Jul 2022 [monthly]

    Recruiting PHASE3

  11. Jan 2022 — Apr 2022 [monthly]

    Recruiting PHASE3

  12. Feb 2021 — Jan 2022 [monthly]

    Recruiting PHASE3

  13. Jan 2021 — Feb 2021 [monthly]

    Recruiting PHASE3

  14. Feb 2020 — Jan 2021 [monthly]

    Recruiting PHASE3

  15. Jan 2020 — Feb 2020 [monthly]

    Recruiting PHASE3

  16. Nov 2019 — Jan 2020 [monthly]

    Recruiting PHASE3

  17. Aug 2019 — Nov 2019 [monthly]

    Recruiting PHASE3

  18. Mar 2019 — Aug 2019 [monthly]

    Recruiting PHASE3

  19. Feb 2019 — Mar 2019 [monthly]

    Recruiting PHASE3

  20. Aug 2018 — Feb 2019 [monthly]

    Recruiting PHASE3

  21. Jun 2018 — Aug 2018 [monthly]

    Recruiting PHASE3

  22. Mar 2018 — Jun 2018 [monthly]

    Recruiting PHASE3

  23. Nov 2017 — Mar 2018 [monthly]

    Recruiting PHASE3

    Status: Not Yet RecruitingRecruiting

  24. Jul 2017 — Nov 2017 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Barmherzige Brüder Vienna
  • Centre Hospitalier Régional de la Citadelle
  • Centre Hospitalier Universitaire Mons
  • Centre Hospitalier Universitaire de Charleroi
  • East Lancashire Hospitals NHS Trust
  • Erasme University Hospital
  • Goethe University
  • Great Western Hospital
  • Guy's and St Thomas' NHS Foundation Trust
  • Heartlands Hospital
  • Hospital Barmherzige Brüder Graz
  • Hospital Barmherzige Brüder St. Veit
  • Johannes Gutenberg University Mainz
  • Johannes Kepler University of Linz
  • KABEG Management
  • Kages
  • Klinikum Klagenfurt am Wörthersee
  • Klinikum rechts der Isar der TUM
  • Krankenhaus Barmherzige Schwestern Linz
  • Landeskrankenhaus Villach
  • Medical University of Graz
  • Medical University of Vienna
  • Mid Yorkshire Teaching NHS Trust
  • Musgrove Park Hospital
  • Nottingham University Hospitals
  • Royal Bolton Hospital NHS Foundation Trust
  • Royal Oldham Hospital
  • Royal Victoria Hospital, Belfast
  • Scunthorpe General Hospital
  • The Queen Elizabeth Hospital
  • University Hospital Kiel
  • University Hospital, Bonn
  • University Hospital, Essen
  • University of Plymouth
  • Wuerzburg University Hospital
Data source: Medical University of Graz

For direct contact, visit the study record on ClinicalTrials.gov .