deltatrials
Completed PHASE2 INTERVENTIONAL 5-arm NCT03191864

Efficacy, Safety, and Pharmacokinetics of APT-1011 in Subjects With Eosinophilic Esophagitis (EoE) (FLUTE)

FLUTicasone in Eosinophilic Esophagitis (FLUTE): A Randomized, Double-blind, Placebo-controlled, Dose-ranging, and Maintenance Study of APT-1011 in Subjects With Eosinophilic Esophagitis

Sponsor: Adare Pharmaceuticals, Inc.

Interventions APT-1011 Placebo
Updated 17 times since 2017 Last updated: Apr 4, 2023 Started: Jun 22, 2017 Primary completion: Jan 3, 2019 Completion: Oct 23, 2019
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT03191864, this PHASE2 trial focuses on Eosinophilic Esophagitis and remains completed. Sponsored by Adare Pharmaceuticals, Inc., it has been updated 17 times since 2017, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Aug 2017 – ~Oct 2017 · 2 months · monthly snapshot~Oct 2017 – ~Dec 2017 · 2 months · monthly snapshot~Dec 2017 – ~Feb 2018 · 2 months · monthly snapshot~Feb 2018 – ~Mar 2018 · 28 days · monthly snapshot~Mar 2018 – ~Jun 2018 · 3 months · monthly snapshot~Jun 2018 – ~Sep 2018 · 3 months · monthly snapshot~Sep 2018 – ~Jan 2019 · 4 months · monthly snapshot~Jan 2019 – ~Mar 2020 · 14 months · monthly snapshot~Mar 2020 – ~Jan 2021 · 10 months · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Mar 2021 · 28 days · monthly snapshot~Mar 2021 – ~Apr 2022 · 13 months · monthly snapshot~Apr 2022 – ~May 2023 · 13 months · monthly snapshot~May 2023 – ~Jul 2024 · 14 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

17 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  4. May 2023 — Jul 2024 [monthly]

    Completed PHASE2

  5. Apr 2022 — May 2023 [monthly]

    Completed PHASE2

Show 12 earlier versions
  1. Mar 2021 — Apr 2022 [monthly]

    Completed PHASE2

  2. Feb 2021 — Mar 2021 [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

  3. Jan 2021 — Feb 2021 [monthly]

    Active Not Recruiting PHASE2

  4. Mar 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE2

  5. Jan 2019 — Mar 2020 [monthly]

    Active Not Recruiting PHASE2

  6. Sep 2018 — Jan 2019 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  7. Jun 2018 — Sep 2018 [monthly]

    Recruiting PHASE2

  8. Mar 2018 — Jun 2018 [monthly]

    Recruiting PHASE2

  9. Feb 2018 — Mar 2018 [monthly]

    Recruiting PHASE2

  10. Dec 2017 — Feb 2018 [monthly]

    Recruiting PHASE2

  11. Oct 2017 — Dec 2017 [monthly]

    Recruiting PHASE2

  12. Aug 2017 — Oct 2017 [monthly]

    Recruiting PHASE2

    First recorded

Jun 2017

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Adare Pharmaceuticals, Inc.
Data source: Adare Pharmaceuticals, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .