Completed PHASE1 INTERVENTIONAL 5-arm NCT03276858

Single and Multiple-Ascending Dose Study of CRN00808 in Healthy Volunteers

A Double-Blind, Randomized, Placebo-Controlled, Single- And-Multiple-Dose Study to Evaluate the Safety, PK, and PD of CRN00808 in Healthy Volunteers and to Determine the Effect of CRN00808 on Midazolam PK

Sponsor: Crinetics Pharmaceuticals Inc.

Conditions Healthy Volunteers

Interventions CRN00808 Midazolam oral solution Placebo Oral Solution Placebo oral capsule

Updated 7 times since 2017 Last updated: Aug 27, 2018 Started: Sep 22, 2017 Primary completion: Apr 30, 2018 Completion: Apr 30, 2018

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1 trial investigates Healthy Volunteers and is currently completed. Crinetics Pharmaceuticals Inc. leads this study, which shows 7 recorded versions since 2017 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

Change History

7 versions recorded

Sep 2024 — Present [monthly]

Completed PHASE1
Jul 2024 — Sep 2024 [monthly]

Completed PHASE1
Jan 2021 — Jul 2024 [monthly]

Completed PHASE1
Sep 2018 — Jan 2021 [monthly]

Completed PHASE1

Status: Recruiting → Completed
Jun 2018 — Sep 2018 [monthly]

Recruiting PHASE1

▶ Show 2 earlier versions

Feb 2018 — Jun 2018 [monthly]

Recruiting PHASE1
Oct 2017 — Feb 2018 [monthly]

Recruiting PHASE1

First recorded

Sep 2017

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Crinetics Pharmaceuticals Inc.

Data source: Crinetics Pharmaceuticals Inc.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Melbourne, Australia