deltatrials
Active Not Recruiting PHASE3 INTERVENTIONAL 2-arm NCT04837040

A Study to Evaluate the Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (PATHFNDR-1)

A Randomized, Controlled, Multi-Center Study to Evaluate the Safety and Efficacy of Paltusotine in Subjects With Acromegaly Treated With Long-acting Somatostatin Receptor Ligands (PATHFNDR-1)

Sponsor: Crinetics Pharmaceuticals Inc.

Conditions Acromegaly
Updated 18 times since 2021 Last updated: Feb 26, 2026 Started: May 12, 2021 Primary completion: Jul 10, 2023 Completion: Jun 30, 2027
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT04837040, this PHASE3 trial focuses on Acromegaly and remains ongoing. Sponsored by Crinetics Pharmaceuticals Inc., it has been updated 18 times since 2021, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~May 2021 – ~Sep 2021 · 4 months · monthly snapshot~Sep 2021 – ~Nov 2021 · 2 months · monthly snapshot~Nov 2021 – ~Feb 2022 · 3 months · monthly snapshot~Feb 2022 – ~Apr 2022 · 59 days · monthly snapshot~Apr 2022 – ~May 2022 · 30 days · monthly snapshot~May 2022 – ~Jul 2022 · 2 months · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Dec 2022 · 3 months · monthly snapshot~Dec 2022 – ~Oct 2023 · 10 months · monthly snapshot~Oct 2023 – ~Apr 2024 · 6 months · monthly snapshot~Apr 2024 – ~Jul 2024 · 3 months · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Jul 2025 · 10 months · monthly snapshot~Jul 2025 – ~Sep 2025 · 2 months · monthly snapshot~Sep 2025 – ~Feb 2026 · 5 months · monthly snapshot~Feb 2026 – ~Mar 2026 · 28 days · monthly snapshot~Mar 2026 – present · 4 months · monthly snapshot

Change History

18 versions recorded
  1. Mar 2026 — Present [monthly]

    Active Not Recruiting PHASE3

  2. Feb 2026 — Mar 2026 [monthly]

    Active Not Recruiting PHASE3

  3. Sep 2025 — Feb 2026 [monthly]

    Active Not Recruiting PHASE3

  4. Jul 2025 — Sep 2025 [monthly]

    Active Not Recruiting PHASE3

  5. Sep 2024 — Jul 2025 [monthly]

    Active Not Recruiting PHASE3

Show 13 earlier versions
  1. Aug 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE3

  2. Jul 2024 — Aug 2024 [monthly]

    Active Not Recruiting PHASE3

  3. Apr 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE3

  4. Oct 2023 — Apr 2024 [monthly]

    Active Not Recruiting PHASE3

  5. Dec 2022 — Oct 2023 [monthly]

    Active Not Recruiting PHASE3

    Status: RecruitingActive Not Recruiting

  6. Sep 2022 — Dec 2022 [monthly]

    Recruiting PHASE3

  7. Jul 2022 — Sep 2022 [monthly]

    Recruiting PHASE3

  8. May 2022 — Jul 2022 [monthly]

    Recruiting PHASE3

  9. Apr 2022 — May 2022 [monthly]

    Recruiting PHASE3

  10. Feb 2022 — Apr 2022 [monthly]

    Recruiting PHASE3

  11. Nov 2021 — Feb 2022 [monthly]

    Recruiting PHASE3

  12. Sep 2021 — Nov 2021 [monthly]

    Recruiting PHASE3

  13. May 2021 — Sep 2021 [monthly]

    Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Crinetics Pharmaceuticals Inc.
Data source: Crinetics Pharmaceuticals Inc.

For direct contact, visit the study record on ClinicalTrials.gov .