deltatrials
Unknown PHASE2/PHASE3 INTERVENTIONAL 2-arm NCT03288870

Efficacy, Safety and Pharmacokinetics of BCD-100 (Anti-PD-1) Monotherapy as Second Line Treatment in Patients With Non-Small Cell Lung Cancer (DOMINUS) (DOMINUS)

International Multi-center Open-label Randomized Clinical Trial of Efficacy, Safety and Pharmacokinetics of BCD-100 (JSC BIOCAD, Russia) Monotherapy Compared to Docetaxel as Second-line Therapy of Patients With Advanced Inoperable or Metastatic Non-small Cell Lung Cancer

Sponsor: Biocad

Updated 11 times since 2017 Last updated: Oct 28, 2020 Started: Sep 19, 2017 Primary completion: Aug 10, 2020 Completion: Aug 10, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2/PHASE3 trial investigates Non Small Cell Lung Cancer Stage IIIB and Non-Small Cell Carcinoma of Lung, TNM Stage 4 and is currently ongoing. Biocad leads this study, which shows 11 recorded versions since 2017 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Oct 2017 – ~Mar 2018 · 5 months · monthly snapshotNot Yet Recruiting~Mar 2018 – ~Jun 2018 · 3 months · monthly snapshotRecruiting~Jun 2018 – ~May 2019 · 11 months · monthly snapshotRecruiting~May 2019 – ~Jun 2019 · 31 days · monthly snapshotActive Not Recruiting~Jun 2019 – ~Nov 2020 · 17 months · monthly snapshotActive Not Recruiting~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshotActive Not Recruiting~Jan 2021 – ~Nov 2022 · 22 months · monthly snapshotActive Not Recruiting~Nov 2022 – ~Jul 2024 · 20 months · monthly snapshotUnknown Status~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotUnknown~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotUnknown~Sep 2025 – present · 10 months · monthly snapshotUnknown

Change History

11 versions recorded
  1. Sep 2025 — Present [monthly]

    Unknown PHASE2/PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Unknown PHASE2/PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Unknown PHASE2/PHASE3

    Status: Unknown StatusUnknown · Phase: PHASE2_PHASE3PHASE2/PHASE3

  4. Nov 2022 — Jul 2024 [monthly]

    Unknown Status PHASE2_PHASE3

    Status: Active Not RecruitingUnknown Status

  5. Jan 2021 — Nov 2022 [monthly]

    Active Not Recruiting PHASE2_PHASE3

Show 6 earlier versions
  1. Nov 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE2_PHASE3

  2. Jun 2019 — Nov 2020 [monthly]

    Active Not Recruiting PHASE2_PHASE3

  3. May 2019 — Jun 2019 [monthly]

    Active Not Recruiting PHASE2_PHASE3

    Status: RecruitingActive Not Recruiting

  4. Jun 2018 — May 2019 [monthly]

    Recruiting PHASE2_PHASE3

  5. Mar 2018 — Jun 2018 [monthly]

    Recruiting PHASE2_PHASE3

    Status: Not Yet RecruitingRecruiting

  6. Oct 2017 — Mar 2018 [monthly]

    Not Yet Recruiting PHASE2_PHASE3

    First recorded

Sep 2017

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Biocad
Data source: Biocad

For direct contact, visit the study record on ClinicalTrials.gov .