deltatrials
Completed PHASE1 INTERVENTIONAL 3-arm NCT03307915

A Study of 2 Different Regimens of Tetravalent Ad26.Mos4.HIV Prime Followed by Boost With Modified Vaccinia Ankara (MVA)-Mosaic OR Ad26.Mos4.HIV Plus a Combination of Mosaic and Clade C gp140 Protein in Human Immunodeficiency Virus (HIV) Type 1 Infected Adults on Suppressive Antiretroviral Treatment

A Safety, Tolerability and Immunogenicity Study of 2 Different Regimens of Tetravalent Ad26.Mos4.HIV Prime Followed by Boost With MVA-Mosaic OR Ad26.Mos4.HIV Plus a Combination of Mosaic and Clade C gp140 Protein in HIV-1 Infected Adults on Suppressive ART

Sponsor: Beth Israel Deaconess Medical Center

Updated 21 times since 2017 Last updated: Jan 31, 2025 Started: Mar 5, 2018 Primary completion: Nov 5, 2021 Completion: Nov 5, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1 clinical study on Human Immunodeficiency Virus, this trial is completed. The trial is conducted by Beth Israel Deaconess Medical Center and has accumulated 21 data snapshots since 2018. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Oct 2017 – ~Nov 2017 · 31 days · monthly snapshot~Nov 2017 – ~Jun 2018 · 7 months · monthly snapshot~Jun 2018 – ~Aug 2018 · 2 months · monthly snapshot~Aug 2018 – ~Nov 2018 · 3 months · monthly snapshot~Nov 2018 – ~Dec 2018 · 30 days · monthly snapshot~Dec 2018 – ~Apr 2019 · 4 months · monthly snapshot~Apr 2019 – ~Jun 2019 · 2 months · monthly snapshot~Jun 2019 – ~Apr 2020 · 10 months · monthly snapshot~Apr 2020 – ~Jul 2020 · 3 months · monthly snapshot~Jul 2020 – ~Sep 2020 · 2 months · monthly snapshot~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshot~Oct 2020 – ~Jan 2021 · 3 months · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Oct 2021 · 8 months · monthly snapshot~Oct 2021 – ~Nov 2021 · 31 days · monthly snapshot~Nov 2021 – ~Dec 2021 · 30 days · monthly snapshot~Dec 2021 – ~Mar 2022 · 3 months · monthly snapshot~Mar 2022 – ~Jul 2024 · 28 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Mar 2025 · 6 months · monthly snapshot~Mar 2025 – present · 16 months · monthly snapshot

Change History

21 versions recorded
  1. Mar 2025 — Present [monthly]

    Completed PHASE1

  2. Sep 2024 — Mar 2025 [monthly]

    Completed PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  4. Mar 2022 — Jul 2024 [monthly]

    Completed PHASE1

    Status: Active Not RecruitingCompleted

  5. Dec 2021 — Mar 2022 [monthly]

    Active Not Recruiting PHASE1

Show 16 earlier versions
  1. Nov 2021 — Dec 2021 [monthly]

    Active Not Recruiting PHASE1

  2. Oct 2021 — Nov 2021 [monthly]

    Active Not Recruiting PHASE1

  3. Feb 2021 — Oct 2021 [monthly]

    Active Not Recruiting PHASE1

  4. Jan 2021 — Feb 2021 [monthly]

    Active Not Recruiting PHASE1

  5. Oct 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE1

  6. Sep 2020 — Oct 2020 [monthly]

    Active Not Recruiting PHASE1

  7. Jul 2020 — Sep 2020 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  8. Apr 2020 — Jul 2020 [monthly]

    Recruiting PHASE1

  9. Jun 2019 — Apr 2020 [monthly]

    Recruiting PHASE1

  10. Apr 2019 — Jun 2019 [monthly]

    Recruiting PHASE1

  11. Dec 2018 — Apr 2019 [monthly]

    Recruiting PHASE1

  12. Nov 2018 — Dec 2018 [monthly]

    Recruiting PHASE1

  13. Aug 2018 — Nov 2018 [monthly]

    Recruiting PHASE1

  14. Jun 2018 — Aug 2018 [monthly]

    Recruiting PHASE1

    Status: Not Yet RecruitingRecruiting

  15. Nov 2017 — Jun 2018 [monthly]

    Not Yet Recruiting PHASE1

  16. Oct 2017 — Nov 2017 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Beth Israel Deaconess Medical Center
  • Janssen Vaccines & Prevention B.V.
  • Ragon Institute of MGH, MIT and Harvard
  • US Military HIV Research Program
Data source: Janssen Vaccines & Prevention B.V.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations