deltatrials
Completed PHASE1 INTERVENTIONAL 1-arm NCT03323658

Bexarotene in Preventing Breast Cancer in Patients at High Risk for Breast Cancer

A Phase I Dose Escalation Study of Topical Bexarotene in Women at High Risk for Breast Cancer

Sponsor: National Cancer Institute (NCI)

Conditions Breast Atypical Ductal Hyperplasia Breast Atypical Lobular Hyperplasia Breast Ductal Carcinoma In Situ Breast Lobular Carcinoma In Situ Invasive Breast Carcinoma
Interventions Bexarotene Questionnaire Administration
Updated 30 times since 2017 Last updated: Dec 13, 2022 Started: Jun 15, 2018 Primary completion: Aug 3, 2021 Completion: Mar 25, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1 trial investigates Breast Atypical Ductal Hyperplasia and Breast Atypical Lobular Hyperplasia and is currently completed. National Cancer Institute (NCI) leads this study, which shows 30 recorded versions since 2018 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Nov 2017 – ~Jun 2018 · 7 months · monthly snapshot~Jun 2018 – ~Aug 2018 · 2 months · monthly snapshot~Aug 2018 – ~Sep 2018 · 31 days · monthly snapshot~Sep 2018 – ~Oct 2018 · 30 days · monthly snapshot~Oct 2018 – ~Mar 2019 · 5 months · monthly snapshot~Mar 2019 – ~Apr 2019 · 31 days · monthly snapshot~Apr 2019 – ~Jun 2019 · 2 months · monthly snapshot~Jun 2019 – ~Jul 2019 · 30 days · monthly snapshot~Jul 2019 – ~Oct 2019 · 3 months · monthly snapshot~Oct 2019 – ~Nov 2019 · 31 days · monthly snapshot~Nov 2019 – ~Jan 2020 · 2 months · monthly snapshot~Jan 2020 – ~Feb 2020 · 31 days · monthly snapshot~Feb 2020 – ~Mar 2020 · 29 days · monthly snapshot~Mar 2020 – ~Apr 2020 · 31 days · monthly snapshot~Apr 2020 – ~May 2020 · 30 days · monthly snapshot~May 2020 – ~Aug 2020 · 3 months · monthly snapshot~Aug 2020 – ~Sep 2020 · 31 days · monthly snapshot~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshot~Oct 2020 – ~Dec 2020 · 2 months · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Apr 2021 · 3 months · monthly snapshot~Apr 2021 – ~Jun 2021 · 2 months · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Apr 2022 · 7 months · monthly snapshot~Apr 2022 – ~Jul 2022 · 3 months · monthly snapshot~Jul 2022 – ~Jan 2023 · 6 months · monthly snapshot~Jan 2023 – ~Feb 2023 · 31 days · monthly snapshot~Feb 2023 – ~Jul 2024 · 17 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 22 months · monthly snapshot

Change History

30 versions recorded

  1. Sep 2024 — Present [monthly]

    Completed PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  3. Feb 2023 — Jul 2024 [monthly]

    Completed PHASE1

    Status: Active Not Recruiting → Completed

  4. Jan 2023 — Feb 2023 [monthly]

    Active Not Recruiting PHASE1

  5. Jul 2022 — Jan 2023 [monthly]

    Active Not Recruiting PHASE1

▶ Show 25 earlier versions

  1. Apr 2022 — Jul 2022 [monthly]

    Active Not Recruiting PHASE1

  2. Sep 2021 — Apr 2022 [monthly]

    Active Not Recruiting PHASE1

    Status: Recruiting → Active Not Recruiting

  3. Jun 2021 — Sep 2021 [monthly]

    Recruiting PHASE1

  4. Apr 2021 — Jun 2021 [monthly]

    Recruiting PHASE1

    Status: Suspended → Recruiting

  5. Jan 2021 — Apr 2021 [monthly]

    Suspended PHASE1

  6. Dec 2020 — Jan 2021 [monthly]

    Suspended PHASE1

  7. Oct 2020 — Dec 2020 [monthly]

    Suspended PHASE1

  8. Sep 2020 — Oct 2020 [monthly]

    Suspended PHASE1

  9. Aug 2020 — Sep 2020 [monthly]

    Suspended PHASE1

  10. May 2020 — Aug 2020 [monthly]

    Suspended PHASE1

  11. Apr 2020 — May 2020 [monthly]

    Suspended PHASE1

  12. Mar 2020 — Apr 2020 [monthly]

    Suspended PHASE1

  13. Feb 2020 — Mar 2020 [monthly]

    Suspended PHASE1

    Status: Recruiting → Suspended

  14. Jan 2020 — Feb 2020 [monthly]

    Recruiting PHASE1

  15. Nov 2019 — Jan 2020 [monthly]

    Recruiting PHASE1

  16. Oct 2019 — Nov 2019 [monthly]

    Recruiting PHASE1

  17. Jul 2019 — Oct 2019 [monthly]

    Recruiting PHASE1

    Status: Suspended → Recruiting

  18. Jun 2019 — Jul 2019 [monthly]

    Suspended PHASE1

    Status: Recruiting → Suspended

  19. Apr 2019 — Jun 2019 [monthly]

    Recruiting PHASE1

  20. Mar 2019 — Apr 2019 [monthly]

    Recruiting PHASE1

  21. Oct 2018 — Mar 2019 [monthly]

    Recruiting PHASE1

  22. Sep 2018 — Oct 2018 [monthly]

    Recruiting PHASE1

  23. Aug 2018 — Sep 2018 [monthly]

    Recruiting PHASE1

    Status: Not Yet Recruiting → Recruiting

  24. Jun 2018 — Aug 2018 [monthly]

    Not Yet Recruiting PHASE1

  25. Nov 2017 — Jun 2018 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • National Cancer Institute (NCI)
Data source: National Cancer Institute (NCI)

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations