deltatrials
Completed PHASE1 INTERVENTIONAL 3-arm NCT03330106

A Study to Evaluate the Effects of Pevonedistat on the Corrected QT (QTc) Interval in Participants With Advanced Solid Tumors

A Randomized, Crossover Phase 1 Study to Evaluate the Effects of Pevonedistat on the QTc Interval in Patients With Advanced Solid Tumors

Sponsor: Millennium Pharmaceuticals, Inc.

Updated 16 times since 2017 Last updated: Jun 13, 2022 Started: Nov 15, 2017 Primary completion: Jan 7, 2019 Completion: Jun 21, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1 clinical study on Advanced Solid Neoplasm, this trial is completed. The trial is conducted by Millennium Pharmaceuticals, Inc. and has accumulated 16 data snapshots since 2017. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Dec 2017 – ~Apr 2018 · 4 months · monthly snapshot~Apr 2018 – ~Jun 2018 · 2 months · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Oct 2018 · 3 months · monthly snapshot~Oct 2018 – ~Aug 2019 · 10 months · monthly snapshot~Aug 2019 – ~Feb 2020 · 6 months · monthly snapshot~Feb 2020 – ~Jan 2021 · 11 months · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Apr 2021 · 59 days · monthly snapshot~Apr 2021 – ~Jun 2021 · 2 months · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Apr 2023 · 19 months · monthly snapshot~Apr 2023 – ~Jul 2024 · 15 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

16 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE1

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  4. Apr 2023 — Jul 2024 [monthly]

    Completed PHASE1

  5. Sep 2021 — Apr 2023 [monthly]

    Completed PHASE1

    Status: Active Not RecruitingCompleted

Show 11 earlier versions
  1. Jun 2021 — Sep 2021 [monthly]

    Active Not Recruiting PHASE1

    Status: CompletedActive Not Recruiting

  2. Apr 2021 — Jun 2021 [monthly]

    Completed PHASE1

    Status: Active Not RecruitingCompleted

  3. Feb 2021 — Apr 2021 [monthly]

    Active Not Recruiting PHASE1

  4. Jan 2021 — Feb 2021 [monthly]

    Active Not Recruiting PHASE1

  5. Feb 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE1

  6. Aug 2019 — Feb 2020 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  7. Oct 2018 — Aug 2019 [monthly]

    Recruiting PHASE1

  8. Jul 2018 — Oct 2018 [monthly]

    Recruiting PHASE1

  9. Jun 2018 — Jul 2018 [monthly]

    Recruiting PHASE1

  10. Apr 2018 — Jun 2018 [monthly]

    Recruiting PHASE1

  11. Dec 2017 — Apr 2018 [monthly]

    Recruiting PHASE1

    First recorded

Nov 2017

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Millennium Pharmaceuticals, Inc.
Data source: Takeda

For direct contact, visit the study record on ClinicalTrials.gov .