deltatrials
Completed PHASE1 INTERVENTIONAL 2-arm NCT03350295

Study Will Evaluate the Relative Bioavailability, Safety, and Tolerability of Single Doses of Nifurtimox 30 mg Tablets Exhibiting Different in Vitro Dissolution Characteristics, and to Evaluate the Relative Bioavailability of Nifurtimox 30 mg and 120 mg

Open Label, Randomized, Single-dose, Cross-over Study to Evaluate the Relative Bioavailability, Safety, and Tolerability of Single Doses of Nifurtimox 30 mg Tablets Exhibiting Different in Vitro Dissolution Characteristics, and to Evaluate the Relative Bioavailability of Nifurtimox 30 mg and 120 mg Tablets, Administered to Adult Male and Female Patients With Chagas' Disease

Sponsor: Bayer

Conditions Chagas Disease
Updated 13 times since 2017 Last updated: Dec 11, 2019 Started: Jun 14, 2018 Primary completion: Sep 18, 2018 Completion: Dec 14, 2018
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1 trial investigates Chagas Disease and is currently completed. Bayer leads this study, which shows 13 recorded versions since 2018 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Dec 2017 – ~Jun 2018 · 6 months · monthly snapshot~Jun 2018 – ~Aug 2018 · 2 months · monthly snapshot~Aug 2018 – ~Sep 2018 · 31 days · monthly snapshot~Sep 2018 – ~Oct 2018 · 30 days · monthly snapshot~Oct 2018 – ~Nov 2018 · 31 days · monthly snapshot~Nov 2018 – ~Dec 2018 · 30 days · monthly snapshot~Dec 2018 – ~Jan 2019 · 31 days · monthly snapshot~Jan 2019 – ~Feb 2019 · 31 days · monthly snapshot~Feb 2019 – ~Jan 2020 · 11 months · monthly snapshot~Jan 2020 – ~Jan 2021 · 12 months · monthly snapshot~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 22 months · monthly snapshot

Change History

13 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  3. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE1

  4. Jan 2020 — Jan 2021 [monthly]

    Completed PHASE1

  5. Feb 2019 — Jan 2020 [monthly]

    Completed PHASE1

    Status: Active Not RecruitingCompleted

Show 8 earlier versions
  1. Jan 2019 — Feb 2019 [monthly]

    Active Not Recruiting PHASE1

  2. Dec 2018 — Jan 2019 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  3. Nov 2018 — Dec 2018 [monthly]

    Recruiting PHASE1

  4. Oct 2018 — Nov 2018 [monthly]

    Recruiting PHASE1

  5. Sep 2018 — Oct 2018 [monthly]

    Recruiting PHASE1

  6. Aug 2018 — Sep 2018 [monthly]

    Recruiting PHASE1

    Status: Not Yet RecruitingRecruiting

  7. Jun 2018 — Aug 2018 [monthly]

    Not Yet Recruiting PHASE1

  8. Dec 2017 — Jun 2018 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Bayer
Data source: Bayer

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations