deltatrials
Completed PHASE3 INTERVENTIONAL 2-arm NCT02625974

A Study to Learn How Well Nifurtimox Works and How Safe it is in Children Aged 0 to 17 Years With Chagas' Disease, an Inflammatory, Infectious Disease Caused by the Parasite Trypanosoma Cruzi

Prospective, Historically Controlled Study to Evaluate the Efficacy and Safety of a New Pediatric Formulation of Nifurtimox in Children Aged 0 to 17 Years With Chagas' Disease

Sponsor: Bayer

Conditions Chagas Disease
Interventions Nifurtimox (Lampit, BAYA2502) Placebo
Updated 37 times since 2017 Last updated: Mar 21, 2024 Started: Jan 27, 2016 Primary completion: Jul 25, 2018 Completion: Aug 10, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT02625974, this PHASE3 trial focuses on Chagas Disease and remains completed. Sponsored by Bayer, it has been updated 37 times since 2016, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Mar 2017 · 28 days · monthly snapshot~Mar 2017 – ~May 2017 · 2 months · monthly snapshot~May 2017 – ~Jun 2017 · 31 days · monthly snapshot~Jun 2017 – ~Jul 2017 · 30 days · monthly snapshot~Jul 2017 – ~Aug 2017 · 31 days · monthly snapshot~Aug 2017 – ~Oct 2017 · 2 months · monthly snapshot~Oct 2017 – ~Feb 2018 · 4 months · monthly snapshot~Feb 2018 – ~Mar 2018 · 28 days · monthly snapshot~Mar 2018 – ~May 2018 · 2 months · monthly snapshot~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Aug 2018 · 31 days · monthly snapshot~Aug 2018 – ~Sep 2018 · 31 days · monthly snapshot~Sep 2018 – ~Oct 2018 · 30 days · monthly snapshot~Oct 2018 – ~Nov 2018 · 31 days · monthly snapshot~Nov 2018 – ~Feb 2019 · 3 months · monthly snapshot~Feb 2019 – ~Apr 2019 · 59 days · monthly snapshot~Apr 2019 – ~Nov 2019 · 7 months · monthly snapshot~Nov 2019 – ~May 2020 · 6 months · monthly snapshot~May 2020 – ~Jun 2020 · 31 days · monthly snapshot~Jun 2020 – ~Jul 2020 · 30 days · monthly snapshot~Jul 2020 – ~Aug 2020 · 31 days · monthly snapshot~Aug 2020 – ~Oct 2020 · 2 months · monthly snapshot~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Dec 2020 · 30 days · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~Apr 2021 · 31 days · monthly snapshot~Apr 2021 – ~May 2021 · 30 days · monthly snapshot~May 2021 – ~Sep 2021 · 4 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Dec 2021 · 2 months · monthly snapshot~Dec 2021 – ~Jul 2024 · 31 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

37 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  4. Dec 2021 — Jul 2024 [monthly]

    Completed PHASE3

  5. Oct 2021 — Dec 2021 [monthly]

    Completed PHASE3

    Status: Active Not Recruiting → Completed

▶ Show 32 earlier versions

  1. Sep 2021 — Oct 2021 [monthly]

    Active Not Recruiting PHASE3

  2. May 2021 — Sep 2021 [monthly]

    Active Not Recruiting PHASE3

  3. Apr 2021 — May 2021 [monthly]

    Active Not Recruiting PHASE3

  4. Mar 2021 — Apr 2021 [monthly]

    Active Not Recruiting PHASE3

  5. Jan 2021 — Mar 2021 [monthly]

    Active Not Recruiting PHASE3

  6. Dec 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE3

  7. Nov 2020 — Dec 2020 [monthly]

    Active Not Recruiting PHASE3

  8. Oct 2020 — Nov 2020 [monthly]

    Active Not Recruiting PHASE3

  9. Aug 2020 — Oct 2020 [monthly]

    Active Not Recruiting PHASE3

  10. Jul 2020 — Aug 2020 [monthly]

    Active Not Recruiting PHASE3

  11. Jun 2020 — Jul 2020 [monthly]

    Active Not Recruiting PHASE3

  12. May 2020 — Jun 2020 [monthly]

    Active Not Recruiting PHASE3

  13. Nov 2019 — May 2020 [monthly]

    Active Not Recruiting PHASE3

  14. Apr 2019 — Nov 2019 [monthly]

    Active Not Recruiting PHASE3

  15. Feb 2019 — Apr 2019 [monthly]

    Active Not Recruiting PHASE3

  16. Nov 2018 — Feb 2019 [monthly]

    Active Not Recruiting PHASE3

  17. Oct 2018 — Nov 2018 [monthly]

    Active Not Recruiting PHASE3

  18. Sep 2018 — Oct 2018 [monthly]

    Active Not Recruiting PHASE3

  19. Aug 2018 — Sep 2018 [monthly]

    Active Not Recruiting PHASE3

  20. Jul 2018 — Aug 2018 [monthly]

    Active Not Recruiting PHASE3

  21. Jun 2018 — Jul 2018 [monthly]

    Active Not Recruiting PHASE3

  22. May 2018 — Jun 2018 [monthly]

    Active Not Recruiting PHASE3

  23. Mar 2018 — May 2018 [monthly]

    Active Not Recruiting PHASE3

  24. Feb 2018 — Mar 2018 [monthly]

    Active Not Recruiting PHASE3

  25. Oct 2017 — Feb 2018 [monthly]

    Active Not Recruiting PHASE3

  26. Aug 2017 — Oct 2017 [monthly]

    Active Not Recruiting PHASE3

    Status: Recruiting → Active Not Recruiting

  27. Jul 2017 — Aug 2017 [monthly]

    Recruiting PHASE3

  28. Jun 2017 — Jul 2017 [monthly]

    Recruiting PHASE3

  29. May 2017 — Jun 2017 [monthly]

    Recruiting PHASE3

  30. Mar 2017 — May 2017 [monthly]

    Recruiting PHASE3

  31. Feb 2017 — Mar 2017 [monthly]

    Recruiting PHASE3

  32. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE3

    First recorded

Jan 2016

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Bayer
Data source: Bayer

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Buenos Aires, Argentina , Cochabamba, Bolivia , Corrientes, Argentina , Floridablabca, Colombia , Formosa, Argentina , La Plata, Argentina , La Rioja, Argentina , Mendoza, Argentina , Posadas, Argentina , Punata, Bolivia and 10 more locations