deltatrials
Unknown PHASE3 INTERVENTIONAL 2-arm NCT03373058

Efficacy of HIPEC in the Treatment of Advanced-Stage Epithelial Ovarian Cancer After Cytoreductive Surgery (EHTASEOCCS)

A Phase III Multicenter Prospective Randomized Controlled Clinical Trial of Hyperthermic Intraperitoneal Chemotherapy in the Treatment of Advanced-Stage Epithelial Ovarian Cancer After Cytoreductive Surgery

Sponsor: Affiliated Cancer Hospital & Institute of Guangzhou Medical University

Conditions Epithelial Ovarian Cancer Fallopian Tube Cancer Primary Peritoneal Carcinoma
Interventions Hyperthermic Intraperitoneal Chemotherapy adjuvant chemotherapy cytoreductive surgery
Updated 14 times since 2017 Last updated: Nov 4, 2019 Started: Oct 15, 2019 Primary completion: Jul 1, 2021 Completion: Jul 1, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT03373058, this PHASE3 trial focuses on Epithelial Ovarian Cancer and Fallopian Tube Cancer and remains ongoing. Sponsored by Affiliated Cancer Hospital & Institute of Guangzhou Medical University, it has been updated 14 times since 2019, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Dec 2017 – ~Jun 2018 · 6 months · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Aug 2018 · 31 days · monthly snapshot~Aug 2018 – ~Dec 2019 · 16 months · monthly snapshot~Dec 2019 – ~Apr 2020 · 4 months · monthly snapshot~Apr 2020 – ~Jan 2021 · 9 months · monthly snapshot~Jan 2021 – ~Oct 2021 · 9 months · monthly snapshot~Oct 2021 – ~Nov 2022 · 13 months · monthly snapshot~Nov 2022 – ~Aug 2023 · 9 months · monthly snapshot~Aug 2023 – ~Jul 2024 · 11 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Aug 2025 · 11 months · monthly snapshot~Aug 2025 – ~Sep 2025 · 31 days · monthly snapshot~Sep 2025 – present · 11 months · monthly snapshot

Change History

14 versions recorded

  1. Sep 2025 — Present [monthly]

    Unknown PHASE3

  2. Aug 2025 — Sep 2025 [monthly]

    Unknown PHASE3

  3. Sep 2024 — Aug 2025 [monthly]

    Unknown PHASE3

  4. Jul 2024 — Sep 2024 [monthly]

    Unknown PHASE3

    Status: Unknown Status → Unknown

  5. Aug 2023 — Jul 2024 [monthly]

    Unknown Status PHASE3

    Status: Recruiting → Unknown Status

▶ Show 9 earlier versions

  1. Nov 2022 — Aug 2023 [monthly]

    Recruiting PHASE3

  2. Oct 2021 — Nov 2022 [monthly]

    Recruiting PHASE3

  3. Jan 2021 — Oct 2021 [monthly]

    Recruiting PHASE3

  4. Apr 2020 — Jan 2021 [monthly]

    Recruiting PHASE3

  5. Dec 2019 — Apr 2020 [monthly]

    Recruiting PHASE3

    Status: Not Yet Recruiting → Recruiting

  6. Aug 2018 — Dec 2019 [monthly]

    Not Yet Recruiting PHASE3

  7. Jul 2018 — Aug 2018 [monthly]

    Not Yet Recruiting PHASE3

  8. Jun 2018 — Jul 2018 [monthly]

    Not Yet Recruiting PHASE3

  9. Dec 2017 — Jun 2018 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Affiliated Cancer Hospital & Institute of Guangzhou Medical University
  • Affiliated Cancer Hospital of Shantou University Medical College
  • Beijing Obstetrics and Gynecology Hospital
  • Cancer Hospital of Guizhou Province
  • Chinese PLA General Hospital
  • Chongqing University Cancer Hospital
  • First Affiliated Hospital of Chongqing Medical University
  • First Affiliated Hospital, Sun Yat-Sen University
  • Fourth Affiliated Hospital of Guangxi Medical University
  • Hebei Medical University Fourth Hospital
  • Henan Cancer Hospital
  • Henan Provincial People's Hospital
  • Obstetrics & Gynecology Hospital of Fudan University
  • Peking Union Medical College Hospital
  • Peking University Cancer Hospital & Institute
  • Peking University People's Hospital
  • RenJi Hospital
  • Shandong Cancer Hospital and Institute
  • Southern Medical University, China
  • Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
  • The Second Hospital of Hebei Medical University
  • The Third Affiliated Hospital of Guangzhou Medical University
  • The Third Xiangya Hospital of Central South University
  • Third Affiliated Hospital, Sun Yat-Sen University
  • Tianjin Medical University Cancer Institute and Hospital
  • Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
  • West China Second University Hospital
  • Wuhan University
  • Xiangya Hospital of Central South University
  • Xinqiao Hospital of Chongqing
Data source: Affiliated Cancer Hospital & Institute of Guangzhou Medical University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations