deltatrials
Completed PHASE2 INTERVENTIONAL 5-arm NCT03373461

Study of Safety and Efficacy of LNP023 in Patients With Kidney Disease Caused by Inflammation

An Adaptive Seamless Randomized, Double-blind, Placebo-controlled, Dose Ranging Study to Investigate the Efficacy and Safety of LNP023 in Primary IgA Nephropathy Patients

Sponsor: Novartis Pharmaceuticals

Conditions IgA Nephropathy
Interventions LNP023 Placebo
Updated 28 times since 2017 Last updated: Jan 27, 2023 Started: Feb 7, 2018 Primary completion: Dec 29, 2020 Completion: Jun 22, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates IgA Nephropathy and is currently completed. Novartis Pharmaceuticals leads this study, which shows 28 recorded versions since 2018 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Dec 2017 – ~Mar 2018 · 3 months · monthly snapshot~Mar 2018 – ~May 2018 · 2 months · monthly snapshot~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Sep 2018 · 3 months · monthly snapshot~Sep 2018 – ~Oct 2018 · 30 days · monthly snapshot~Oct 2018 – ~Nov 2018 · 31 days · monthly snapshot~Nov 2018 – ~Dec 2018 · 30 days · monthly snapshot~Dec 2018 – ~Feb 2019 · 2 months · monthly snapshot~Feb 2019 – ~Jun 2019 · 4 months · monthly snapshot~Jun 2019 – ~Nov 2019 · 5 months · monthly snapshot~Nov 2019 – ~Feb 2020 · 3 months · monthly snapshot~Feb 2020 – ~Mar 2020 · 29 days · monthly snapshot~Mar 2020 – ~Apr 2020 · 31 days · monthly snapshot~Apr 2020 – ~Jun 2020 · 2 months · monthly snapshot~Jun 2020 – ~Oct 2020 · 4 months · monthly snapshot~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Dec 2020 · 30 days · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Apr 2021 · 3 months · monthly snapshot~Apr 2021 – ~Jun 2021 · 2 months · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Apr 2022 · 7 months · monthly snapshot~Apr 2022 – ~Nov 2022 · 7 months · monthly snapshot~Nov 2022 – ~Feb 2023 · 3 months · monthly snapshot~Feb 2023 – ~Jul 2024 · 17 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 11 months · monthly snapshot

Change History

28 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  4. Feb 2023 — Jul 2024 [monthly]

    Completed PHASE2

  5. Nov 2022 — Feb 2023 [monthly]

    Completed PHASE2

▶ Show 23 earlier versions

  1. Apr 2022 — Nov 2022 [monthly]

    Completed PHASE2

  2. Sep 2021 — Apr 2022 [monthly]

    Completed PHASE2

    Status: Active Not Recruiting → Completed

  3. Jun 2021 — Sep 2021 [monthly]

    Active Not Recruiting PHASE2

  4. Apr 2021 — Jun 2021 [monthly]

    Active Not Recruiting PHASE2

    Status: Recruiting → Active Not Recruiting

  5. Jan 2021 — Apr 2021 [monthly]

    Recruiting PHASE2

  6. Dec 2020 — Jan 2021 [monthly]

    Recruiting PHASE2

  7. Nov 2020 — Dec 2020 [monthly]

    Recruiting PHASE2

  8. Oct 2020 — Nov 2020 [monthly]

    Recruiting PHASE2

  9. Jun 2020 — Oct 2020 [monthly]

    Recruiting PHASE2

  10. Apr 2020 — Jun 2020 [monthly]

    Recruiting PHASE2

  11. Mar 2020 — Apr 2020 [monthly]

    Recruiting PHASE2

  12. Feb 2020 — Mar 2020 [monthly]

    Recruiting PHASE2

  13. Nov 2019 — Feb 2020 [monthly]

    Recruiting PHASE2

  14. Jun 2019 — Nov 2019 [monthly]

    Recruiting PHASE2

  15. Feb 2019 — Jun 2019 [monthly]

    Recruiting PHASE2

  16. Dec 2018 — Feb 2019 [monthly]

    Recruiting PHASE2

  17. Nov 2018 — Dec 2018 [monthly]

    Recruiting PHASE2

  18. Oct 2018 — Nov 2018 [monthly]

    Recruiting PHASE2

  19. Sep 2018 — Oct 2018 [monthly]

    Recruiting PHASE2

  20. Jun 2018 — Sep 2018 [monthly]

    Recruiting PHASE2

  21. May 2018 — Jun 2018 [monthly]

    Recruiting PHASE2

    Status: Not Yet Recruiting → Recruiting

  22. Mar 2018 — May 2018 [monthly]

    Not Yet Recruiting PHASE2

  23. Dec 2017 — Mar 2018 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Novartis Pharmaceuticals
Data source: Novartis

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Aalborg, Denmark , Ankara, Turkey (Türkiye) , Arhus N, Denmark , Ashkelon, Israel , Bangkok, Thailand , Barranquilla, Colombia , Beijing, China , Bergen, Norway , Berlin, Germany , Caba, Argentina and 42 more locations