deltatrials
Recruiting PHASE3 INTERVENTIONAL 1-arm NCT04557462

A Rollover Extension Program (REP) to Evaluate the Long-term Safety and Tolerability of Open Label Iptacopan/LNP023 in Participants With Primary IgA Nephropathy

A Multicenter Rollover Extension Program (REP) to Evaluate the Long-term Safety and Tolerability of Open Label Iptacopan in Adult Participants With Primary IgA Nephropathy Who Have Completed Study CLNP023X2203 or CLNP023A2301

Sponsor: Novartis Pharmaceuticals

Interventions LNP023
Updated 25 times since 2020 Last updated: Feb 19, 2026 Started: Sep 20, 2021 Primary completion: Oct 25, 2032 Completion: Oct 25, 2032
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Primary IgA Nephropathy and is currently actively recruiting participants. Novartis Pharmaceuticals leads this study, which shows 25 recorded versions since 2021 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Oct 2020 – ~Jan 2021 · 3 months · monthly snapshot~Jan 2021 – ~Apr 2021 · 3 months · monthly snapshot~Apr 2021 – ~Sep 2021 · 5 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Sep 2022 · 11 months · monthly snapshot~Sep 2022 – ~Jun 2023 · 9 months · monthly snapshot~Jun 2023 – ~Jul 2023 · 30 days · monthly snapshot~Jul 2023 – ~Aug 2023 · 31 days · monthly snapshot~Aug 2023 – ~Dec 2023 · 4 months · monthly snapshot~Dec 2023 – ~Jan 2024 · 31 days · monthly snapshot~Jan 2024 – ~Mar 2024 · 2 months · monthly snapshot~Mar 2024 – ~May 2024 · 2 months · monthly snapshot~May 2024 – ~Jul 2024 · 2 months · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Jan 2025 · 3 months · monthly snapshot~Jan 2025 – ~Apr 2025 · 3 months · monthly snapshot~Apr 2025 – ~May 2025 · 30 days · monthly snapshot~May 2025 – ~Jun 2025 · 31 days · monthly snapshot~Jun 2025 – ~Jul 2025 · 30 days · monthly snapshot~Jul 2025 – ~Sep 2025 · 2 months · monthly snapshot~Sep 2025 – ~Jan 2026 · 4 months · monthly snapshot~Jan 2026 – ~Feb 2026 · 31 days · monthly snapshot~Feb 2026 – present · 6 months · monthly snapshot

Change History

25 versions recorded
  1. Feb 2026 — Present [monthly]

    Recruiting PHASE3

  2. Jan 2026 — Feb 2026 [monthly]

    Recruiting PHASE3

  3. Sep 2025 — Jan 2026 [monthly]

    Recruiting PHASE3

  4. Jul 2025 — Sep 2025 [monthly]

    Recruiting PHASE3

  5. Jun 2025 — Jul 2025 [monthly]

    Recruiting PHASE3

Show 20 earlier versions
  1. May 2025 — Jun 2025 [monthly]

    Recruiting PHASE3

  2. Apr 2025 — May 2025 [monthly]

    Recruiting PHASE3

  3. Jan 2025 — Apr 2025 [monthly]

    Recruiting PHASE3

  4. Oct 2024 — Jan 2025 [monthly]

    Recruiting PHASE3

  5. Sep 2024 — Oct 2024 [monthly]

    Recruiting PHASE3

  6. Aug 2024 — Sep 2024 [monthly]

    Recruiting PHASE3

  7. Jul 2024 — Aug 2024 [monthly]

    Recruiting PHASE3

  8. May 2024 — Jul 2024 [monthly]

    Recruiting PHASE3

  9. Mar 2024 — May 2024 [monthly]

    Recruiting PHASE3

  10. Jan 2024 — Mar 2024 [monthly]

    Recruiting PHASE3

  11. Dec 2023 — Jan 2024 [monthly]

    Recruiting PHASE3

  12. Aug 2023 — Dec 2023 [monthly]

    Recruiting PHASE3

  13. Jul 2023 — Aug 2023 [monthly]

    Recruiting PHASE3

  14. Jun 2023 — Jul 2023 [monthly]

    Recruiting PHASE3

  15. Sep 2022 — Jun 2023 [monthly]

    Recruiting PHASE3

  16. Oct 2021 — Sep 2022 [monthly]

    Recruiting PHASE3

    Status: Not Yet RecruitingRecruiting

  17. Sep 2021 — Oct 2021 [monthly]

    Not Yet Recruiting PHASE3

  18. Apr 2021 — Sep 2021 [monthly]

    Not Yet Recruiting PHASE3

  19. Jan 2021 — Apr 2021 [monthly]

    Not Yet Recruiting PHASE3

  20. Oct 2020 — Jan 2021 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Novartis Pharmaceuticals
Data source: Novartis

For direct contact, visit the study record on ClinicalTrials.gov .