deltatrials
Terminated PHASE2 INTERVENTIONAL 1-arm NCT03417739

A Phase II Study of BVD-523 in Metastatic Uveal Melanoma

Sponsor: BioMed Valley Discoveries, Inc

Conditions Uveal Melanoma
Interventions BVD-523
Updated 16 times since 2018 Last updated: Feb 21, 2026 Started: Mar 26, 2018 Primary completion: May 5, 2020 Completion: Jul 16, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

This was a Simon two stage design trial that terminated after the first stage due to lack of response.

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Browse all Uveal Melanoma trials

A PHASE2 clinical study on Uveal Melanoma, this trial is terminated or withdrawn. The trial is conducted by BioMed Valley Discoveries, Inc and has accumulated 16 data snapshots since 2018. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Feb 2018 – ~May 2018 · 3 months · monthly snapshot~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Sep 2018 · 3 months · monthly snapshot~Sep 2018 – ~Apr 2019 · 7 months · monthly snapshot~Apr 2019 – ~May 2019 · 30 days · monthly snapshot~May 2019 – ~Jul 2020 · 14 months · monthly snapshot~Jul 2020 – ~Jan 2021 · 6 months · monthly snapshot~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshot~Sep 2021 – ~Dec 2021 · 3 months · monthly snapshot~Dec 2021 – ~Dec 2022 · 12 months · monthly snapshot~Dec 2022 – ~Mar 2023 · 3 months · monthly snapshot~Mar 2023 – ~Dec 2023 · 9 months · monthly snapshot~Dec 2023 – ~Jul 2024 · 7 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Feb 2026 · 17 months · monthly snapshot~Feb 2026 – present · 5 months · monthly snapshot

Change History

16 versions recorded

  1. Feb 2026 — Present [monthly]

    Terminated PHASE2

    Status: Active Not Recruiting → Terminated

  2. Sep 2024 — Feb 2026 [monthly]

    Active Not Recruiting PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE2

  4. Dec 2023 — Jul 2024 [monthly]

    Active Not Recruiting PHASE2

  5. Mar 2023 — Dec 2023 [monthly]

    Active Not Recruiting PHASE2

▶ Show 11 earlier versions

  1. Dec 2022 — Mar 2023 [monthly]

    Active Not Recruiting PHASE2

  2. Dec 2021 — Dec 2022 [monthly]

    Active Not Recruiting PHASE2

  3. Sep 2021 — Dec 2021 [monthly]

    Active Not Recruiting PHASE2

  4. Jan 2021 — Sep 2021 [monthly]

    Active Not Recruiting PHASE2

  5. Jul 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE2

  6. May 2019 — Jul 2020 [monthly]

    Active Not Recruiting PHASE2

    Status: Recruiting → Active Not Recruiting

  7. Apr 2019 — May 2019 [monthly]

    Recruiting PHASE2

  8. Sep 2018 — Apr 2019 [monthly]

    Recruiting PHASE2

  9. Jun 2018 — Sep 2018 [monthly]

    Recruiting PHASE2

  10. May 2018 — Jun 2018 [monthly]

    Recruiting PHASE2

    Status: Not Yet Recruiting → Recruiting

  11. Feb 2018 — May 2018 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • BioMed Valley Discoveries, Inc
  • Dana-Farber Cancer Institute
Data source: Dana-Farber Cancer Institute

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations